Protein Alignment Alg11 and PIGA

DIOPT Version :9

• Sequence 1: NP_001262182.1
• Gene: Alg11 / 40402
• FlyBaseID: FBgn0037108
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_002632.1
• Gene: PIGA / 5277
• HGNCID: 8957
• Length: 484
• Species: Homo sapiens
• Alignment Length: 433
• Identity: 85/433 - (19%)
• Similarity: 160/433 - (36%)
• Gaps: 117/433 - (27%)

  Fly    89 SPNSILQKAKNVFNIAVDSDNVKFVFLKQRHWIEAKNYPHFTLLGQSI---GSMVV--------- 141
            ||.|:........||.:.||    .|......:|:    |...|.|.:   |..|:
Human    21 SPGSLYTCRTRTHNICMVSD----FFYPNMGGVES----HIYQLSQCLIERGHKVIIVTHAYGNR 77

  Fly   142 -GLEALCRFPPDIYIDTMGYAFTY-PLFRYLAQSKVGCYVHYPVISTDMLKRVQQRQ---MSHNN 201
             |:..|          |.|....| ||.....||......|    |..:|:.:..|:   :.|::
Human    78 KGIRYL----------TSGLKVYYLPLKVMYNQSTATTLFH----SLPLLRYIFVRERVTIIHSH 128

  Fly   202 KKYVARNPFLTWTKLAYYRLFSRMYKWVGCCAETIMVNSSWTENHILQLWDV-PFKTHRVYPP-- 263
            ..:.|         :|:..||.         |:|:.:.:.:|::.:....|| ...|:::...
Human   129 SSFSA---------MAHDALFH---------AKTMGLQTVFTDHSLFGFADVSSVLTNKLLTVSL 175

  Fly   264 CEVSHLKSLQHTEKGDEFI-------ILSV-------GQFRPEKDHPLQLQAIYELRTLLAQDEA 314
            |:.:|:..:.:|.|.:..:       |:||       ..|.|:   |.:.   ::..|::.....
Human   176 CDTNHIICVSYTSKENTVLRAALNPEIVSVIPNAVDPTDFTPD---PFRR---HDSITIVVVSRL 234

  Fly   315 LWNQ----IKLVIVGSCRNEDDYERLKN--------MQDLTKHLSLENNVQFSVNVPYEDLLKLY 367
            ::.:    :..:|...|:...|...:..        ::::.:...|.:.|:....:.::|:..:.
Human   235 VYRKGIDLLSGIIPELCQKYPDLNFIIGGEGPKRIILEEVRERYQLHDRVRLLGALEHKDVRNVL 299

  Fly   368 QTAHIGIHTMWNEHFGIGIVESMAAGLIMVAHKSGG-------PLLDIVETSA-----GSQNGF- 419
            ...||.::|...|.|.:.|||:.:.||.:|:.:.||       .|:.:.|.|.     |.:...
Human   300 VQGHIFLNTSLTEAFCMAIVEAASCGLQVVSTRVGGIPEVLPENLIILCEPSVKSLCEGLEKAIF 364

  Fly   420 -LATDAVEYAENILNIIVNNSEMNGIRNAA--------RASVE 453
             |.:..:...|||.||:   ......||.|        |.|||
Human   365 QLKSGTLPAPENIHNIV---KTFYTWRNVAERTEKVYDRVSVE 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alg11	NP_001262182.1	PLN02949	24..473	CDD:215511	85/433 (20%)
		GT1_ALG11_like	44..463	CDD:99978	85/433 (20%)
PIGA	NP_002632.1	GT1_PIG-A_like	34..432	CDD:99970	82/420 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0438
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810