DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alg11 and alg11

DIOPT Version :9

Sequence 1:	NP_001262182.1	Gene:	Alg11 / 40402	FlyBaseID:	FBgn0037108	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_989283.1	Gene:	alg11 / 394898	XenbaseID:	XB-GENE-5934131	Length:	487	Species:	Xenopus tropicalis

Alignment Length:	477	Identity:	236/477 - (49%)
Similarity:	307/477 - (64%)	Gaps:	14/477 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LFLFLLWLLLSLVLVAVLSFLFLRQWLLGRKNKLHTSSENGIN---VGIFHPYCNAGGGGERVLW 64
            ||:.:|...:.|.||.||.|:..|.|:..:|.:.....::|..   |..||||||||||||||||
Frog    17 LFIPVLIASIGLCLVLVLLFICTRLWIQRKKKQSVEIGKDGKKKRVVAFFHPYCNAGGGGERVLW 81

  Fly    65 CAVRALQEKYQNARMVIYTGDIDASPNSILQKAKNVFNIAVDSDNVKFVFLKQRHWIEAKNYPHF 129
            ||:|:||::|::|..||||||.|.|...||..|...|||.: |..|||:||::|..:||..||.|
Frog    82 CALRSLQKRYKDAIYVIYTGDKDVSEEQILNGAAARFNIKL-SHPVKFIFLEKRGLVEASFYPRF 145

  Fly   130 TLLGQSIGSMVVGLEALCRFPPDIYIDTMGYAFTYPLFRYLAQSKVGCYVHYPVISTDMLKRVQQ 194
            ||||||:||:|:|.|||.:..||||||:||||||.|||:|:...:||||||||.||.|||..|:.
Frog   146 TLLGQSLGSVVLGWEALTKCVPDIYIDSMGYAFTLPLFKYVGGCQVGCYVHYPTISMDMLSVVRS 210

  Fly   195 RQMSHNNKKYVARNPFLTWTKLAYYRLFSRMYKWVGCCAETIMVNSSWTENHILQLWDVPFKTHR 259
            :....||..:::.||.|:..||.||.||:.:|.|||.|::.|||||:||..|||.||....:|..
Frog   211 QNARFNNAAFISNNPVLSRLKLIYYYLFAVIYGWVGSCSDVIMVNSTWTFAHILDLWKCSERTSI 275

  Fly   260 VYPPCEVSHLKSL---QHTEKGDEFIILSVGQFRPEKDHPLQLQAIYELRTLLAQDEALWNQIKL 321
            |||||:|.....:   ||.:. :|..|:|:||||||||||||:.|   ...||.:......::||
Frog   276 VYPPCDVQTFLDINLNQHKDI-EEHSIVSIGQFRPEKDHPLQICA---FAALLKKKTTEKLKLKL 336

  Fly   322 VIVGSCRNEDDYERLKNMQDLTKHLSLENNVQFSVNVPYEDLLKLYQTAHIGIHTMWNEHFGIGI 386
            :::|.|||.:|..|:..::.|:..|.:.  |:|.||:|:.:|.|....|.||:||||||||||||
Frog   337 ILIGGCRNNEDELRVSELKKLSSELGIP--VEFKVNIPFAELKKHLSEATIGLHTMWNEHFGIGI 399

  Fly   387 VESMAAGLIMVAHKSGGPLLDIVETSAGSQNGFLATDAVEYAENILNIIVNNSEMN-GIRNAARA 450
            ||.||||.|::||.||||.||||......:.||||.....||..:..|:....|.. .||..||.
Frog   400 VECMAAGTIILAHNSGGPKLDIVVPYEEHETGFLADSVESYAAAMDYILCLTPEQRLTIRQNARR 464

  Fly   451 SVERFSEQEFEKNFLRAVSTLF 472
            ||.|||:||||.|||.:...||
Frog   465 SVARFSDQEFEANFLASSEPLF 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg11	NP_001262182.1	PLN02949	24..473	CDD:215511	227/456 (50%)
Alg11	NP_001262182.1	GT1_ALG11_like	44..463	CDD:99978	218/425 (51%)
alg11	NP_989283.1	GT4_ALG11-like	61..477	CDD:340835	218/422 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	251	1.000	Domainoid score	I2056
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68893
Inparanoid	1	1.050	434	1.000	Inparanoid score	I1664
OMA	1	1.010	-	-		QHG53627
OrthoDB	1	1.010	-	-		D1051021at2759
OrthoFinder	1	1.000	-	-		FOG0004723
OrthoInspector	1	1.000	-	-		oto103136
Panther	1	1.100	-	-	LDO	PTHR45919
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R38
SonicParanoid	1	1.000	-	-		X3321
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110