Protein Alignment Alg11 and GYS1

DIOPT Version :9

• Sequence 1: NP_001262182.1
• Gene: Alg11 / 40402
• FlyBaseID: FBgn0037108
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_002094.2
• Gene: GYS1 / 2997
• HGNCID: 4706
• Length: 737
• Species: Homo sapiens
• Alignment Length: 537
• Identity: 113/537 - (21%)
• Similarity: 179/537 - (33%)
• Gaps: 188/537 - (35%)

  Fly    29 LLGRKNKLHTSSENGINVGIFHPYCNAGGGGE-RVLWCAVRALQE----------KYQNARMVIY 82
            :|..|.|: |..|.|.|..:..||...|...: .:|.....||:.          |....|.:|.
Human    46 VLQTKAKV-TGDEWGDNYFLVGPYTEQGVRTQVELLEAPTPALKRTLDSMNSKGCKVYFGRWLIE 109

  Fly    83 TG------DIDASPNSILQKAK----NVFNIAVD------SDNVKFVFLKQRHWI------EAKN 125
            .|      |:.||..: |::.|    :..||.|.      :|.|.|.||..  |.      :::.
Human   110 GGPLVVLLDVGASAWA-LERWKGELWDTCNIGVPWYDREANDAVLFGFLTT--WFLGEFLAQSEE 171

  Fly   126 YPHFT------LLGQSIGSMVVGLEALC---RFPPDIYIDTMGYAFTYPLFRYLAQSKVGCYVHY 181
            .||..      |.|       ||| .||   |.|    :.|:.......|.|||....|..|.:.
Human   172 KPHVVAHFHEWLAG-------VGL-CLCRARRLP----VATIFTTHATLLGRYLCAGAVDFYNNL 224

  Fly   182 PVISTDMLKRVQQRQMSHNNKKYVARNPFLTWTKLAYYRLFSRMYKWVGCCAETIMVNSSWTENH 246
            ...:.|  |...:||:.|   :|                           |.|....:.:    |
Human   225 ENFNVD--KEAGERQIYH---RY---------------------------CMERAAAHCA----H 253

  Fly   247 ILQLWDVPFKTHRVYPPCEVSHLKSL--QHTEKGDEFII----LSVGQFRPEKDHPLQLQAIYEL 305
            :       |.|        ||.:.::  ||..|....|:    |:|.:|          .|::|.
Human   254 V-------FTT--------VSQITAIEAQHLLKRKPDIVTPNGLNVKKF----------SAMHEF 293

  Fly   306 RTLLAQDEALWNQIKLVIVGSCRNEDDYERLKNMQDLTKHLSLENNVQFS---VNVPYEDLLKL- 366
            :.|.||.:|   :|:..:.|......|:    |: |.|.:..:....:||   .:|..|.|.:|
Human   294 QNLHAQSKA---RIQEFVRGHFYGHLDF----NL-DKTLYFFIAGRYEFSNKGADVFLEALARLN 350

  Fly   367 -------------------YQTAHIGIHT---------MWN------EHFGIGIVESMAAGLIMV 397
                               .:|.:..:.|         :|:      |.||..:.||:..|.:..
Human   351 YLLRVNGSEQTVVAFFIMPARTNNFNVETLKGQAVRKQLWDTANTVKEKFGRKLYESLLVGSLPD 415

  Fly   398 AHKSGGPLLDIVETSAGSQNGFLATDAVEY----AENIL----NIIVNNSEMNGIRNAARASVER 454
            .:|    :|| .|.....:....||....:    ..|:|    :.|:......|:.|::...|:.
Human   416 MNK----MLD-KEDFTMMKRAIFATQRQSFPPVCTHNMLDDSSDPILTTIRRIGLFNSSADRVKV 475

  Fly   455 FSEQEFEKNFLRAVSTL 471
            .    |...||.:.|.|
Human   476 I----FHPEFLSSTSPL 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alg11	NP_001262182.1	PLN02949	24..473	CDD:215511	113/537 (21%)
		GT1_ALG11_like	44..463	CDD:99978	103/512 (20%)
GYS1	NP_002094.2	Glycogen_syn	31..663	CDD:283373	113/537 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	634..737

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0438
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900