DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Alg11 and Alg1

DIOPT Version :9

Sequence 1:NP_001262182.1 Gene:Alg11 / 40402 FlyBaseID:FBgn0037108 Length:475 Species:Drosophila melanogaster
Sequence 2:XP_036015739.1 Gene:Alg1 / 208211 MGIID:2384774 Length:536 Species:Mus musculus


Alignment Length:591 Identity:105/591 - (17%)
Similarity:174/591 - (29%) Gaps:210/591 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 LVLVAVLSFLFLRQWLLGRKN--------------------KLHTSS--ENGINVGIFHPYCNAG 56
            |||..:|..|.|..|..||:.                    :.|..|  ::|.:|.:...|....
Mouse     9 LVLALLLLVLLLGLWKRGRQTGRARHMVVVVLGDVGRSPRMQYHALSLAQSGFSVTLLGFYSEWR 73

  Fly    57 G---------------GGERVLWCAVRAL--------------------------QEKYQNARM- 79
            |               |..|...|:..|.                          .|..||.|: 
Mouse    74 GPEREAQSGALTLPVLGQRREQLCSSPACSGLDRCFLVSGSSGRQSPFTIHSKPRDELLQNDRIR 138

  Fly    80 VIYTGD---IDASPNSILQKAKNVFNIA------VDSDNVKFVFLKQRHWIEAKNYPHFTLLGQS 135
            ::...|   :.|.|..:....|.||...      :..|...::||        :|.|        
Mouse   139 IVKLTDLRGLGAGPRILQYGVKVVFQAVYLLWKMMRMDPAAYIFL--------QNPP-------- 187

  Fly   136 IGSMVVGLEAL-------CRFPPDIYIDTMGYAFTYPLFRYLAQSKVGCYVHYPVISTDMLKRVQ 193
                  ||.|:       |.....:.||...|.:          |.:| .||.|           
Mouse   188 ------GLPAIAVCWFVGCICGSKLVIDWHNYGY----------SIMG-LVHGP----------- 224

  Fly   194 QRQMSHNNKKYVARNPFLTWTKLAYYRLFSRMYKWVGCCAETIMVNSSWTEN---HILQLWDVP- 254
                         |:|.:...|. |.:.|.|: ..:..|....| .....||   ..:.|:|.| 
Mouse   225 -------------RHPIVLLAKW-YEKFFGRL-SHLNLCVTNAM-REDLAENWCVRAVTLYDKPA 273

  Fly   255 ---------------FKTHRVYPPCEVSHLKSLQHTEK-----------------GDEFIILSVG 287
                           .|....|.|.:.....|...||:                 |...:::|..
Mouse   274 SFFKETPLDLQHELFMKLSHTYSPFQSCSDPSHPDTERSAFTERDCQSGVVRRLHGRPALLVSST 338

  Fly   288 QFRPEKDHPLQLQAIYELRTLLAQDEALWNQIKLVIVGSCRNEDDYERLKNMQDLTKHLSLENNV 352
            .:..::|..:.|:|:.:........::| ..:..||.|.....:.|..|.:.    |||   .:|
Mouse   339 SWTEDEDFSILLRALEKFEQQALTGDSL-PSLVCVITGKGPLREHYRHLISQ----KHL---QHV 395

  Fly   353 QFSVNVPY---EDLLKLYQTAHIGI--HTMWNEHFGIGIVESMAAGLIMVAHKSGGPLLDIV--- 409
            :|.  .|:   ||...|..:|.:|:  |           :.|....|.|......|..|.:.   
Mouse   396 RFC--TPWLEAEDYPLLLGSADLGVCLH-----------MSSSGLDLPMKVVDMFGCHLPVCAVN 447

  Fly   410 -----ETSAGSQNGFLATDAVEYAENILNIIVNNSEMNGIRNAARASVERFSEQEFEKNFLRAVS 469
                 |.....:||.:..||.|.|..:..:.....:..|..:..|..::...:|.:::::...|.
Mouse   448 FKCLHELVRHGENGLVFKDAEELAAQLQMLFSKFPDPAGKLSQFRKKLQESGQQRWDESWQHTVL 512

  Fly   470 TLFTNN 475
            .|..::
Mouse   513 PLLAHS 518

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Alg11NP_001262182.1 PLN02949 24..473 CDD:215511 100/577 (17%)
GT1_ALG11_like 44..463 CDD:99978 91/525 (17%)
Alg1XP_036015739.1 GT33_ALG1-like 33..515 CDD:340843 95/562 (17%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0438
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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