DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7166 and Igsf9

DIOPT Version :9

Sequence 1:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001139272.1	Gene:	Igsf9 / 93842	MGIID:	2135283	Length:	1179	Species:	Mus musculus

Alignment Length:	333	Identity:	82/333 - (24%)
Similarity:	130/333 - (39%)	Gaps:	70/333 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 WTLVLYLFSFSLS----------------------LIGGSFILPENDPPTTAPKFLSRGHLYKVI 51
            |.|.|.:.|..:|                      ::|...:.|...||....::|..|.|..:.
Mouse     3 WCLRLTVLSLIISQGADGRRKPEVVSVVGRAGESAVLGCDLLPPAGHPPLHVIEWLRFGFLLPIF 67

  Fly    52 VGETIELPCKVQNLGSFVLLWRKGSSVLTAGHLKITRDQ--RFKIVGDYNLQINGVKTQDAGDYI 114
            :...:..|                         :|..|.  |.::....:|||.|::.:|.|.|.
Mouse    68 IQFGLYSP-------------------------RIDPDYVGRVRLQTGASLQIEGLRVEDQGWYE 107

  Fly   115 CQL--GDQENRDQ-------VHTVEILVPPTLRALPHNGQVTARKGSTVTLECKASGNPVPTIFW 170
            |::  .||.:.:|       || :.:..||..:..|.. .:..::...|||.|.|.|:|.|.:.|
Mouse   108 CRVLFLDQHSPEQDFANGSWVH-LTVNSPPQFQETPPL-VLEVKELEAVTLRCVARGSPQPYVTW 170

  Fly   171 -FK-KDVFSGPTHLS-DSSTLILENVDRHHAGTYQCSADNGVKDRVSMDIQLTILSPPEITVEKS 232
             |: :|:..|...:. .:.||.:..|:|..||.|.|.|.:. :..::...||.:|.||.|.|..|
Mouse   171 KFRGQDLGKGQGQVQVQNGTLWIRRVERGSAGDYTCQASSS-EGSITHATQLLVLGPPVIVVPPS 234

  Fly   233 WVHASEGYDVELVCIVHG-DVNSEMLWYQ---NSFLLDATDRRSMYPRDDRYSLIIRNFQPTDFG 293
            ....:...||.|.|.... ..|....|:|   |.|.:.....|.....|.  ||.::..||.|.|
Mouse   235 NSTVNSSQDVSLACRAEAYPANLTYSWFQDGVNVFHISRLQSRVRILVDG--SLWLQATQPDDAG 297

  Fly   294 NYSCVADN 301
            :|:||..|
Mouse   298 HYTCVPSN 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	17/93 (18%)
		Ig	56..116	CDD:143165	11/61 (18%)
		IG_like	144..221	CDD:214653	23/79 (29%)
		IGc2	151..209	CDD:197706	21/60 (35%)
		IG_like	232..313	CDD:214653	22/74 (30%)
		Ig	242..311	CDD:143165	20/64 (31%)
Igsf9	NP_001139272.1	IG_like	28..110	CDD:214653	19/106 (18%)
		Ig	136..223	CDD:386229	25/88 (28%)
		Ig_3	227..305	CDD:372822	24/79 (30%)
		Ig	341..404	CDD:386229
		Ig	436..500	CDD:319273
		FN3	508..599	CDD:238020
		FN3	625..715	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	767..807
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	819..842
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	942..974
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1016..1079
		PDZ-binding	1177..1179
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810