DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7166 and Siglece

DIOPT Version :9

Sequence 1:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_006541381.1	Gene:	Siglece / 83382	MGIID:	1932475	Length:	520	Species:	Mus musculus

Alignment Length:	343	Identity:	81/343 - (23%)
Similarity:	130/343 - (37%)	Gaps:	85/343 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 KVIV--GETIELPCKVQNLGSFVLLW-----------------RKGSSVLTAGHL----KITRDQ 90
            ||:|  |..:.:||....|...:..|                 ||.|.|.|...:    |.||:
Mouse    32 KVVVQEGLCVLVPCNFSYLKKRLTDWTDSDPVHGFWYREGTDRRKDSIVATNNPIRKAVKETRN- 95

  Fly    91 RFKIVG-----DYNLQINGVKTQDAGDYICQLGDQENR-----DQV--------HTVEILVPPTL 137
            ||.::|     |.:|.|..::.:|||.|..:|...:.:     |::        :|.:||:|.||
Mouse    96 RFFLLGDPWRNDCSLNIREIRKKDAGLYFFRLERGKTKYNYMWDKMTLVVTALTNTPQILLPETL 160

  Fly   138 RALPHNGQVTARKGSTVTLECKASGNPVPTIF-WFKKDVFSGPTHLSDSSTLILENVDRHHAGTY 201
            .| .|...:|.    :|..:|   |...|.|| |....|....|:.:.||.|.:....:.|....
Mouse   161 EA-GHPSNLTC----SVPWDC---GWTAPPIFSWTGTSVSFLSTNTTGSSVLTITPQPQDHGTNL 217

  Fly   202 QCSAD-NGVKDRVSMDIQLTI-LSPPEITV--------------EKSWVHASEGYDVELVCIVHG 250
            .|... .|......|.|:|.: .:|..:||              ..|.:..|||..:.|:|....
Mouse   218 TCQVTLPGTNVSTRMTIRLNVSYAPKNLTVTIYQGADSVSTILKNGSSLPISEGQSLRLICSTDS 282

  Fly   251 DVNSEMLW-YQNSFL----LDATDRRSMYPRDDRYSLIIRNFQPTDFGNYSCVADNALGRTKKYI 310
            ...:.:.| :.|..|    |.......::|...::.           |.|:|.|.:|||  .::|
Mouse   283 YPPANLSWSWDNLTLCPSKLSKPGLLELFPVHLKHG-----------GVYTCQAQHALG--SQHI 334

  Fly   311 EVSGRPGPADFISPALSG 328
            .:|..|..:..:|..:.|
Mouse   335 SLSLSPQSSATLSEMMMG 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	29/123 (24%)
		Ig	56..116	CDD:143165	22/85 (26%)
		IG_like	144..221	CDD:214653	19/78 (24%)
		IGc2	151..209	CDD:197706	14/59 (24%)
		IG_like	232..313	CDD:214653	19/85 (22%)
		Ig	242..311	CDD:143165	14/73 (19%)
Siglece	XP_006541381.1	Ig	25..146	CDD:386229	28/114 (25%)
		Ig	152..225	CDD:386229	22/80 (28%)
		Ig_3	264..326	CDD:372822	14/72 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000