DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7166 and igsf9bb

DIOPT Version :9

Sequence 1:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_009293693.1	Gene:	igsf9bb / 569554	ZFINID:	ZDB-GENE-091112-15	Length:	1439	Species:	Danio rerio

Alignment Length:	419	Identity:	115/419 - (27%)
Similarity:	169/419 - (40%)	Gaps:	92/419 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 TLVLYLFSFSLSLIGGSFILPENDPPTTAPKFL-SRGHLYKVIVGETIELPCKV---QNLGSFVL 70
            ||:..:||...:...|:..:.|.      |:|: ||       .|||:.|.|.|   .|...:|:
Zfish     7 TLIASVFSTRGTAAQGAHGVREE------PQFVTSR-------AGETVILGCDVVHPLNGQPYVV 58

  Fly    71 LWRK-GSSV-------LTAGHLKITRDQRFKIVGDYNLQINGVKTQDAGDYICQLGDQENRDQVH 127
            .|.| |..:       ....|:......|..:.|..:|:|..|:::|.|.|.|::...|  .|.|
Zfish    59 EWFKFGVPIPFFINFRFYPPHVDPEYAGRASLHGKSSLRIERVRSEDQGWYECKVLMLE--QQYH 121

  Fly   128 T--------VEILVPPTLRALPHNGQVTARKGSTVTLECKASGNPVPTIFWFKKDVFSGPTH--- 181
            |        :.:..|||....|.. .|.|::|.::||.|.|.|||.|::.|.::   ..|..
Zfish   122 TFHNGSWVHLTVNAPPTFTDTPPQ-YVEAKEGGSITLSCTAFGNPKPSVSWLRE---GNPVQDST 182

  Fly   182 ---LSDSSTLILENVDRHHAGTYQCSADNGVKDRVSMDIQLT-----ILSPPE-ITVEKSWVHAS 237
               :||.| |.|.::.|...|.|.|.|.:...:.|.....|.     |:|||| |||..|
Zfish   183 KYKVSDGS-LTLVSISREDRGAYTCRAYSEQGEAVHTTRLLVQGPPFIVSPPENITVNIS----- 241

  Fly   238 EGYDVELVCIVH---GDVNSEMLWYQ-NSFLLDATDRRSMYPRDDRYSLIIRNFQPTDFGNYSCV 298
              .|....|...   |::.....|.: |.|..:...||.....|.  ||||...:|.|.|.|:|.
Zfish   242 --QDAFFTCQAEAYPGNLTYTWFWEEDNVFFKNDLKRRVSILIDG--SLIISQVKPEDAGKYTCS 302

  Fly   299 ADNALGR--------TKKY-IEVSGRPGPADFISPALSGFLDHYNLTWTIESIPPLDEIKLLYRR 354
            ..|:|||        |..| ..|...| |..:::..|.|:     :...:::.||:..:|.....
Zfish   303 PSNSLGRPPSASAYLTVHYPARVINMP-PVIYVAIGLPGY-----IRCPVDANPPVTSVKWKKDG 361

  Fly   355 L-LMNETYQHPGKWHEYHIKPTPIRTDGS 382
            | |..|.|  || |.:..        |||
Zfish   362 LPLRIEKY--PG-WSQME--------DGS 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	25/101 (25%)
		Ig	56..116	CDD:143165	17/70 (24%)
		IG_like	144..221	CDD:214653	25/87 (29%)
		IGc2	151..209	CDD:197706	21/63 (33%)
		IG_like	232..313	CDD:214653	25/93 (27%)
		Ig	242..311	CDD:143165	23/81 (28%)
igsf9bb	XP_009293693.1	IG_like	30..113	CDD:214653	25/89 (28%)
		Ig	41..113	CDD:143165	18/71 (25%)
		IG_like	144..223	CDD:214653	24/83 (29%)
		IGc2	151..208	CDD:197706	20/60 (33%)
		I-set	227..319	CDD:254352	31/100 (31%)
		Ig	<263..319	CDD:299845	19/57 (33%)
		Ig_2	326..414	CDD:290606	17/71 (24%)
		IG_like	329..403	CDD:214653	17/68 (25%)
		IG_like	424..504	CDD:214653
		Ig	440..504	CDD:299845
		FN3	509..604	CDD:238020
		FN3	620..704	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910