DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7166 and aebp1b

DIOPT Version :9

Sequence 1:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_696022.6	Gene:	aebp1b / 567630	ZFINID:	ZDB-GENE-030131-8546	Length:	1247	Species:	Danio rerio

Alignment Length:	346	Identity:	79/346 - (22%)
Similarity:	114/346 - (32%)	Gaps:	89/346 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 VGETIELPCKV----QNLGSFVLLW--RKGSSVLTA-GHLKITRDQRFKIVGDY--NLQINGVKT 107
            ||:..:|.|||    :|:.     |  ..|..|||. |:||:...      |..  :|.:.....
Zfish    69 VGQHKQLLCKVSSDAKNIN-----WVSPNGEKVLTKHGNLKVHNH------GSVLSSLTVLNANL 122

  Fly   108 QDAGDYICQL--GDQENRDQVHTVEILVPPTLRALPHNGQVTARKGSTVTLECKASGNPVPTIFW 170
            .:||.|.|..  ||.|::..| .::|::....|.       |.|||....|:     .|.|:
Zfish   123 NNAGIYKCVATNGDTESQATV-KLDIILKRMRRD-------TDRKGREKRLK-----EPKPS--- 171

  Fly   171 FKKDVFSGPTHLSDSSTLILENVDRHHAGTYQCSADNGVKDRVSMDIQLTILSPPEITVEKSWVH 235
             ||...|.||....|     |...:...|    ....|.|:|.......|....|..||...:
Zfish   172 -KKPKASKPTKKPKS-----EKKGKGEKG----GKKKGKKNREESTTVATTTVAPTTTVPMEY-- 224

  Fly   236 ASEGYDVELVCIVHGDVNSEMLWYQNSFLLDATDRRSMYPRDDRYSLIIRNFQPTDFGNYSCVAD 300
             .|.||.|.......|..:|......:........:...|..|.||      ||..:.:|..|.:
Zfish   225 -EEFYDPEPDQYWDEDFPAETTTVARTTTTPTEKTKDFIPDMDEYS------QPDSYDDYWKVDE 282

  Fly   301 NALGRTKKYIEVSGRPGPADFISPA----------------LSGFLDHYNLTWTIE-SIPPLDEI 348
                .|.....::|||...|....|                :|...:.:..|.|.| ::||.:
Zfish   283 ----PTPTTSVIAGRPADDDDYWDARSVEMVENLPFPDGKEISSTDNDWQYTTTEEPTVPPFE-- 341

  Fly   349 KLLYRRLLMNETYQHPGKWHE 369
                     |..|:.....||
Zfish   342 ---------NSWYEEYEYGHE 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	26/91 (29%)
		Ig	56..116	CDD:143165	18/68 (26%)
		IG_like	144..221	CDD:214653	18/76 (24%)
		IGc2	151..209	CDD:197706	12/57 (21%)
		IG_like	232..313	CDD:214653	15/80 (19%)
		Ig	242..311	CDD:143165	12/68 (18%)
aebp1b	XP_696022.6	Ig	56..147	CDD:299845	25/89 (28%)
		IG_like	62..145	CDD:214653	25/87 (29%)
		FA58C	402..555	CDD:238014
		FA58C	403..556	CDD:214572
		Peptidase_M14_like	577..1036	CDD:299699
		Peptidase_M14NE-CP-C_like	1040..1115	CDD:200604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900