DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7166 and pvrl2l

DIOPT Version :9

Sequence 1:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_017207738.1	Gene:	pvrl2l / 560933	ZFINID:	ZDB-GENE-060503-249	Length:	508	Species:	Danio rerio

Alignment Length:	460	Identity:	98/460 - (21%)
Similarity:	161/460 - (35%)	Gaps:	121/460 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 TIELPCKVQNLGSFVLL---W--------RKGSSVL------------TAGHLKITRDQRFKIVG 96
            ::.|.|:..|.|:..|.   |        |:..:|.            ..|.:|.|:..    :.
Zfish    41 SVNLRCEFTNSGTTKLTQVSWMFERAENDRQNIAVFHPQYGASFPNKDFEGRVKFTQGS----LE 101

  Fly    97 DYNLQINGVKTQDAGDYICQLGDQENRDQVHTVEILVPPTLRALPHNG--QVTARKGST--VTLE 157
            :.:::|:.::..|||.|||:.....:.::..|..::    :.|.|.|.  .:..|.|::  |...
Zfish   102 NPSIRIDKLRMADAGRYICEYATYPSGNEQGTTTLI----MLAKPKNSATAIPVRAGTSEVVVAT 162

  Fly   158 CKAS-GNPVPTIFWFKKDVFSGPTHLS---DSSTLILENVDRHHAGTYQCSADNG------VKDR 212
            |.|: |.|..||.|. ..:.....|.|   ...|:.:::..|    ......:||      |..|
Zfish   163 CAAAQGKPEATISWI-TTITGRYNHTSVPESDGTVTVKSEYR----MIPTPVENGKEITCVVNQR 222

  Fly   213 VSMD-----IQLTILSPPEITVEKSWVHASEGY---------DVELVCIVHGDVN---SEMLWYQ 260
            ..|:     ::|.:..||.:|:        :||         ||.|.|  ..|.|   ||:.|
Zfish   223 TQMEDKVFNLKLVVEYPPTVTI--------DGYDNNWYMGRTDVYLTC--EADANPEPSEISW-- 275

  Fly   261 NSFLLDATDRRSMYPRDDRYSLIIRNFQPTDFGNYSCVADNALGRTKK-----YIEVSGRPGPAD 320
                ..||.:.....|.:...|::|....|....:.|...|.||..||     .||.:..|..|.
Zfish   276 ----TVATGQMPSSVRVEENRLLVRKVDETVNTTFVCEVKNRLGTGKKELVALVIESTEDPSSAG 336

  Fly   321 FISPALSGFLDHYNLTWTIESIPPLDEIKLLYRRLLMNETYQHPGKWHEYHIKPTPIRTDGSHFL 385
            .::.|:.|            |...|..:..|...|:|....|.    |.|       ..||...:
Zfish   337 VVAGAILG------------SFLALVLVGALVTVLIMRSRRQQ----HGY-------SADGEQSV 378

  Fly   386 MSYLVKNLEHNAVYEAIVQAKNKYGWNEISDIHQFYTRNHDLLLDIDMEYKMGISSNIRISPTVS 450
            ..      ....::.....:||..|.|....|:.:...:...|.:...|:....||    :||..
Zfish   379 YG------NKTRLFGGKKSSKNGAGANNNGPIYTYRESDPGALTEKCNEFPHMTSS----TPTAH 433

  Fly   451 GIILS 455
            .|:||
Zfish   434 DILLS 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	19/100 (19%)
		Ig	56..116	CDD:143165	17/82 (21%)
		IG_like	144..221	CDD:214653	20/95 (21%)
		IGc2	151..209	CDD:197706	15/69 (22%)
		IG_like	232..313	CDD:214653	25/97 (26%)
		Ig	242..311	CDD:143165	20/76 (26%)
pvrl2l	XP_017207738.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	42	1.000	Domainoid score	I12424
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000