DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7166 and lrit1a

DIOPT Version :9

Sequence 1:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001018174.2	Gene:	lrit1a / 553943	ZFINID:	ZDB-GENE-040924-5	Length:	643	Species:	Danio rerio

Alignment Length:	178	Identity:	45/178 - (25%)
Similarity:	66/178 - (37%)	Gaps:	43/178 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 CKVQNLGSFVLLWRKGSSVLTAGHLKITRDQRFKIVGDYNLQINGVKTQDAGDYICQLGDQENRD 124
            |::.:|..|    :|..|:..|     ..|.|.:.....:|  :||...||....||      ..
Zfish   205 CRLYDLVQF----QKSPSLSVA-----FIDTRLRCADPESL--SGVLFSDAELRRCQ------GP 252

  Fly   125 QVHTVEILVPPTLRALPHNGQVTARKGSTVTLECKASGNPVPTIFWFKKD--VFSGPTHLSDS-- 185
            :|||..             .:|.:..|:.|.|.|...|.|:|.:.|.:.|  ..:|...|.:|
Zfish   253 RVHTAV-------------ARVRSAVGNNVLLRCGTVGVPIPELAWRRADGKPLNGTVLLENSKE 304

  Fly   186 ----STLILENVDRHHAGTYQCSADN--GVKDRVSMDIQLTILSPPEI 227
                |.|.:..|.....|.|.|.|.|  |..:.|   |.|.|...|::
Zfish   305 GIVWSILSVPAVSYRDTGKYICKATNYAGSAEAV---ISLIINDAPKM 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	18/72 (25%)
		Ig	56..116	CDD:143165	13/55 (24%)
		IG_like	144..221	CDD:214653	25/86 (29%)
		IGc2	151..209	CDD:197706	20/67 (30%)
		IG_like	232..313	CDD:214653
		Ig	242..311	CDD:143165
lrit1a	NP_001018174.2	leucine-rich repeat	61..84	CDD:275378
		LRR_8	63..119	CDD:290566
		LRR_RI	<77..175	CDD:238064
		leucine-rich repeat	85..108	CDD:275378
		LRR_8	108..167	CDD:290566
		leucine-rich repeat	109..132	CDD:275378
		leucine-rich repeat	133..156	CDD:275378
		leucine-rich repeat	157..170	CDD:275378
		LRRCT	199..243	CDD:214507	11/48 (23%)
		I-set	252..343	CDD:254352	28/106 (26%)
		Ig	259..333	CDD:299845	21/73 (29%)
		fn3	448..515	CDD:278470
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900