DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7166 and KIRREL1

DIOPT Version :9

Sequence 1:NP_001262181.1 Gene:CG7166 / 40401 FlyBaseID:FBgn0037107 Length:467 Species:Drosophila melanogaster
Sequence 2:XP_005245362.1 Gene:KIRREL1 / 55243 HGNCID:15734 Length:773 Species:Homo sapiens


Alignment Length:363 Identity:88/363 - (24%)
Similarity:133/363 - (36%) Gaps:66/363 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 LSLIGGSFILPENDPPTTAPKFLSRGHLYKVIVGETIELPCKVQNLGSFVLLWRKGSSVLTAGH- 83
            |||:.....|.:.....|..:|........|:.|:...|||.:.|. |.::.|.|....|..|. 
Human     2 LSLLVWILTLSDTFSQGTQTRFSQEPADQTVVAGQRAVLPCVLLNY-SGIVQWTKDGLALGMGQG 65

  Fly    84 LKITRDQRFKIV-----GDYNLQINGVKTQDAGDYICQLGDQENRDQVHTVEILVPPTLRALPHN 143
            ||..  .|:::|     |.|||:|...:..|...|.||..:...|.:...:.:|:||....:...
Human    66 LKAW--PRYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEDTRIDGG 128

  Fly   144 GQVTARKGSTVTLECKA-SGNPVPTIFWFK-----KDVFSGPTHLSDS------STLILENVDRH 196
            ..:..:.|:...|.|:| :..|..||.||:     :...:....|.|.      |.|::...|..
Human   129 PVILLQAGTPHNLTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLD 193

  Fly   197 HAGTYQC-SADNGVKDRVSMDIQLTILSPPEITVEKSWVHASEGYDVELVCIVHGDVNSEML--- 257
            ....:.| |.:..:.......|:|.:..||.:|:........||..|...|  ....|.|:|   
Human   194 IGRVFTCRSMNEAIPSGKETSIELDVHHPPTVTLSIEPQTVQEGERVVFTC--QATANPEILGYR 256

  Fly   258 WYQNSFLL-DATDRRSMYPRDDRYSLIIRNFQPTDFGNYSCVADNALGRTK----------KYIE 311
            |.:..||: ||.:.|  |..:..||...   :|.     ||...|.:|.|.          ..|.
Human   257 WAKGGFLIEDAHESR--YETNVDYSFFT---EPV-----SCEVHNKVGSTNVSTLVNVHFAPRIV 311

  Fly   312 VSGRPGPADFIS-----------PALSGFLDHYNLTWT 338
            |..:|...|..|           |.|:       ||||
Human   312 VDPKPTTTDIGSDVTLTCVWVGNPPLT-------LTWT 342

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7166NP_001262181.1 IG_like 50..133 CDD:214653 25/88 (28%)
Ig 56..116 CDD:143165 20/65 (31%)
IG_like 144..221 CDD:214653 18/89 (20%)
IGc2 151..209 CDD:197706 16/70 (23%)
IG_like 232..313 CDD:214653 23/94 (24%)
Ig 242..311 CDD:143165 20/82 (24%)
KIRREL1XP_005245362.1 I-set 22..116 CDD:254352 26/96 (27%)
Ig 25..116 CDD:299845 25/93 (27%)
Ig2_KIRREL3-like 138..219 CDD:143236 17/80 (21%)
I-set 223..304 CDD:254352 24/92 (26%)
Ig_2 227..305 CDD:290606 22/89 (25%)
Ig_2 311..405 CDD:290606 10/39 (26%)
IG_like 314..405 CDD:214653 9/36 (25%)
Ig5_KIRREL3 407..504 CDD:143306
IG_like 416..504 CDD:214653
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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