DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7166 and iglon5

DIOPT Version :9

Sequence 1:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001017775.2	Gene:	iglon5 / 550472	ZFINID:	ZDB-GENE-050417-297	Length:	332	Species:	Danio rerio

Alignment Length:	319	Identity:	88/319 - (27%)
Similarity:	137/319 - (42%)	Gaps:	31/319 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 GHL---YKVIVGETIELPCKVQNLGSFVLLWRKGSSVLTAGHLKITRDQRFKIV----GDYNLQI 102
            |||   ..|:.||::.|.||:....:. ..|...|::|..|..|.:.|.|..:.    .|::::|
Zfish    30 GHLPDNITVLEGESVVLRCKIDEEVTH-KAWLNRSNILFTGTDKWSLDSRVSLENNNNSDFSIRI 93

  Fly   103 NGVKTQDAGDYICQLGDQENRDQVHTVEILVPPTLRALPHNGQVTARKGSTVTLECKASGNPVPT 167
            ..|...|.|.|.|.. ...|:.:...|.::|....|.:..:...:..:|..|.|.|.|.|.|.||
Zfish    94 ERVMVADEGPYTCSF-QARNKPRTAHVYLIVQVPARIVNISQDKSVNEGEDVNLFCLAVGRPEPT 157

  Fly   168 IFWFKKDVFSGPTHLSDSSTLILENVDRHHAGTYQCSADNGVKDRVSMDIQLTILSPPEITVEKS 232
            |.|  ||...|  .|::...|.:..:.||.|..::|..:|||....:..:::|:..||.||..|:
Zfish   158 ITW--KDFKYG--LLNEGEFLEITEIKRHQAEDFECITNNGVAPPDTRKVKVTVNYPPIITDVKN 218

  Fly   233 WVHASEGYDVELVCIVHGDVNSEMLWYQNSFLLDATDRR--------SMYPRDDRYSLIIRNFQP 289
             :.|..|....|.|.......:...||::       |||        .:.....|..|:..|...
Zfish   219 -MPAQVGKTAILRCEAMAVPTASFEWYRD-------DRRPVESDNTLKIKNEKTRSLLLFTNVTE 275

  Fly   290 TDFGNYSCVADNALGRTKKYIEVSGRPGPADFISPALSGFLDHYNLTWTIESIPPLDEI 348
            ..||||:|.|.|.||.:...: :..|||.....:.:|:|.|....| |...||..|.::
Zfish   276 KHFGNYTCFASNRLGASNASM-LLFRPGAVYGGAASLNGRLSGVGL-WFCLSISVLMKV 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	22/86 (26%)
		Ig	56..116	CDD:143165	16/63 (25%)
		IG_like	144..221	CDD:214653	23/76 (30%)
		IGc2	151..209	CDD:197706	21/57 (37%)
		IG_like	232..313	CDD:214653	21/88 (24%)
		Ig	242..311	CDD:143165	19/76 (25%)
iglon5	NP_001017775.2	IG_like	33..123	CDD:214653	22/91 (24%)
		Ig	35..123	CDD:299845	22/89 (25%)
		Ig	125..>183	CDD:299845	18/61 (30%)
		I-set	128..207	CDD:254352	24/82 (29%)
		IG_like	217..298	CDD:214653	22/89 (25%)
		ig	223..296	CDD:278476	20/79 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	118	1.000	Inparanoid score	I4772
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.960