DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7166 and dpr6

DIOPT Version :9

Sequence 1:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001287018.1	Gene:	dpr6 / 50296	FlyBaseID:	FBgn0040823	Length:	396	Species:	Drosophila melanogaster

Alignment Length:	254	Identity:	67/254 - (26%)
Similarity:	103/254 - (40%)	Gaps:	60/254 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 WTLVLYLFSFSLSLIGG------------------------SFILPENDPPTTA---PKFL---- 42
            |.|:|.:...|....||                        :.:||  ..||.|   ||::
  Fly    13 WLLLLVVIVMSDMTNGGVQGPIEGYNSLDDLLTTTPTPGQAALLLP--TAPTAAYTHPKWMEPYF 75

  Fly    43 --SRGHLYKVIVGETIELPCKVQNLGSFVLLW--RKGSSVLTAGHLKITRDQRFKI-----VGDY 98
              |.......::|::..|.|:|:||.:..:.|  .:...:||.|....|.||||:.     ..|:
  Fly    76 DPSTPRNVTALMGKSAYLSCRVRNLANKTVSWIRHRDIHILTVGSYTYTSDQRFQATHHQDTEDW 140

  Fly    99 NLQINGVKTQDAGDYICQLGDQENRDQVHTVEILVP-PTLRALPHNGQVTARKGSTVTLECKASG 162
            .|||...:.:|||.|.||:..|..|.....:.::|| .|:...|   .:...||||:.|.|....
  Fly   141 TLQIKWAQKRDAGMYECQISTQPVRSYFVRLNVVVPTATILGGP---DLHVDKGSTINLTCTVKF 202

  Fly   163 NPVPT--IFWF----------KKDVFSGPTHLSDSST--LILENVDRHHAGTYQCSADN 207
            :|.|.  |||:          .:...|..|...|.:|  |:::|.|...:|.|.|:..|
  Fly   203 SPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDVTTSFLLIQNADLADSGKYSCAPSN 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	27/89 (30%)
		Ig	56..116	CDD:143165	22/66 (33%)
		IG_like	144..221	CDD:214653	22/78 (28%)
		IGc2	151..209	CDD:197706	21/71 (30%)
		IG_like	232..313	CDD:214653
		Ig	242..311	CDD:143165
dpr6	NP_001287018.1	V-set	79..174	CDD:284989	27/94 (29%)
		IG_like	80..175	CDD:214653	27/94 (29%)
		IG_like	184..271	CDD:214653	23/81 (28%)
		IGc2	191..262	CDD:197706	21/71 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	42	1.000	Domainoid score	I12424
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810