DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7166 and CG13506

DIOPT Version :9

Sequence 1:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster

Alignment Length:	449	Identity:	111/449 - (24%)
Similarity:	189/449 - (42%)	Gaps:	75/449 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 GETIELPCKVQNLG-SFVLLWRKGSSVLTAGHLKITRDQRFKIVGDYNLQINGVKTQDAGDYICQ 116
            |:.:.|.|..:|.. |..::|.|...::..|...|:  ||.:.:.:.::.:..|..:|:.||.|:
  Fly    84 GDDVILNCDARNFQLSNAVVWYKNRIIIANGQNPIS--QRVQCMLNNSILLRNVSPEDSDDYYCE 146

  Fly   117 LGDQENRDQVHTVEILVPPTLRALPHNGQV-----TARKGSTVTLECKASGNPVPTIFWFKKDVF 176
            :..|..|.  ||. :.|...|..|..:..:     |.|:|....|||:.......||.|...|:.
  Fly   147 ILPQRVRQ--HTA-LRVGARLSILCDDRDITDRSQTFRQGDHHKLECRTYLPDNATIKWSFNDLN 208

  Fly   177 SGPTHL-SDSSTLILENVDRHHAGTYQCSADNGVK----DRVSMDIQLTILSPPEITVEKSWVHA 236
            ..|:.: :.:..:||:|||..:||.|||.||:|.:    ..|.:|:|.:    |.::..:..|:.
  Fly   209 GQPSSVDNQNGVIILDNVDEKNAGDYQCLADDGSRHPPHGTVHIDVQYS----PIVSTHRHNVNT 269

  Fly   237 SEGYDVELVCIVHGDVNSEMLWYQNSFLLDATDRRSM----YPRDDRYSLIIRNFQPTDFGNYSC 297
            .:|...||.|...........:.::...|..:|:.|:    :...:|.:||:|....:|.|.|.|
  Fly   270 EKGATAELYCNYRAKPIGRSYFIKDGKTLQLSDKYSLKDSVHNDHNRTTLIVREVTDSDLGEYLC 334

  Fly   298 VADNALGRTKKYIEVSGRPGPADFISPALSGFLDHYNLTWTIESIPPLDEIKLLYR--------R 354
            ..:||:|..:..:.||..|....|....:.|  :...|.|.:.|...|.|..|.|:        .
  Fly   335 QVENAIGSNEVKVHVSYNPETPQFEDMTVEG--NKVTLHWLVRSHQLLSEAMLDYQLTGSYTWST 397

  Fly   355 LLMNETYQHPGK---WHEYHIKPTPIRTDGSHFLMSYLVKNLE-HNAVYEAIVQAKNKYGWNEIS 415
            :.:.||::|...   |...|                    .|| ...|:.|.|:.||..||:..|
  Fly   398 VQVLETHRHNNTDNIWKITH--------------------QLELSRGVWHARVKTKNTKGWSHFS 442

  Fly   416 DIHQF-------YTRNHDLLLDIDMEYKMGI--------SSNIRISPTVSGIILSAFIL 459
            :.|.|       ..::.::.|..|...:.||        ||..|::  |..|:|:|.:|
  Fly   443 NDHVFEIPEDSEVDKDEEVELPPDEIVQAGIMPMSKGAASSMQRLN--VGVILLAALLL 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	20/80 (25%)
		Ig	56..116	CDD:143165	14/60 (23%)
		IG_like	144..221	CDD:214653	27/86 (31%)
		IGc2	151..209	CDD:197706	21/58 (36%)
		IG_like	232..313	CDD:214653	19/84 (23%)
		Ig	242..311	CDD:143165	17/72 (24%)
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	15/63 (24%)
		IGc2	83..146	CDD:197706	15/63 (24%)
		IG_like	176..254	CDD:214653	25/77 (32%)
		Ig	176..239	CDD:299845	21/62 (34%)
		I-set	258..349	CDD:254352	20/90 (22%)
		Ig	275..348	CDD:143165	17/72 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45080
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910