DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG7166 and Lac

DIOPT Version :9

Sequence 1:NP_001262181.1 Gene:CG7166 / 40401 FlyBaseID:FBgn0037107 Length:467 Species:Drosophila melanogaster
Sequence 2:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster


Alignment Length:284 Identity:82/284 - (28%)
Similarity:130/284 - (45%) Gaps:30/284 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    52 VGETIELPCKVQNLGSFVLLWRKGSS---VLTAGHLKITRDQRFKIVGD-----YNLQINGVKTQ 108
            :|.|:|..|.||....:.:|:.|..|   .|:.|...:.:|.||.:..|     |.|||..::..
  Fly    42 IGGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQET 106

  Fly   109 DAGDYICQLGDQENRDQVHTVEILVPPTLRALP-----HNGQVTARKGSTVTLECKASGNPVPTI 168
            |||.|.||:    ....||.|...|..::|..|     ....|.|.:||.|.:||.|||.|.|||
  Fly   107 DAGTYTCQV----VISTVHKVSAEVKLSV
RRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTI 167

  Fly   169 FWFKKDVFSGPTHLSDSSTLI-----LENVDRHHAGTYQCSADNGVKDRVSMDIQLTILSPPEIT 228
            .|.:::....||   ||:|.:     :::|.:...|||.|.|||||......:|.:.:...|.||
  Fly   168 TWRRENNAILPT---DSATYVGNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNINVEVEFAPVIT 229

  Fly   229 VEKSWVHASEGYDVELVCIVHGDVNSEMLWYQNSFLLDATDRRSM--YPRDDRY---SLIIRNFQ 288
            |.:..:..:..||::|.|.:.......::|.::...|......|:  :...|.|   :|.:...:
  Fly   230 VPRPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDSTLRVITVE 294

  Fly   289 PTDFGNYSCVADNALGRTKKYIEV 312
            ...:|:|.|.|.|..|..:..:.:
  Fly   295 KRQYGDYVCKATNRFGEAEARVNL 318

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7166NP_001262181.1 IG_like 50..133 CDD:214653 28/88 (32%)
Ig 56..116 CDD:143165 21/67 (31%)
IG_like 144..221 CDD:214653 31/81 (38%)
IGc2 151..209 CDD:197706 26/62 (42%)
IG_like 232..313 CDD:214653 16/86 (19%)
Ig 242..311 CDD:143165 14/73 (19%)
LacNP_523713.2 IG_like 36..131 CDD:214653 29/92 (32%)
FR1 37..50 CDD:409353 3/7 (43%)
Ig strand A' 37..42 CDD:409353 82/284 (29%)
Ig strand B 44..51 CDD:409353 2/6 (33%)
CDR1 51..59 CDD:409353 2/7 (29%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 3/13 (23%)
Ig strand C' 68..72 CDD:409353 0/3 (0%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 12/30 (40%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 4/7 (57%)
Ig strand F 108..115 CDD:409353 4/6 (67%)
CDR3 116..124 CDD:409353 2/7 (29%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 27/76 (36%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 2/3 (67%)
Ig strand E 187..191 CDD:409353 0/3 (0%)
Ig strand F 201..206 CDD:409353 3/4 (75%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 19/90 (21%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 1/3 (33%)
Ig strand F 300..305 CDD:409353 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X97
32.810

Return to query results.
Submit another query.