DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG7166 and Sdk2

DIOPT Version :9

Sequence 1:NP_001262181.1 Gene:CG7166 / 40401 FlyBaseID:FBgn0037107 Length:467 Species:Drosophila melanogaster
Sequence 2:XP_006247755.1 Gene:Sdk2 / 360652 RGDID:1310397 Length:2175 Species:Rattus norvegicus


Alignment Length:433 Identity:103/433 - (23%)
Similarity:163/433 - (37%) Gaps:110/433 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 YWTLVLYLFSFSLSLIGGSFILPENDPP--TTAPKFLSRGHLYKVIVGETIELPCKVQNLGSFVL 70
            |:.....|.|.|::.:.....|...:||  ...|:......:.||     :::||:.:.:....:
  Rat   284 YYECEAMLRSSSVAPVTRGAYLSVLEPPQFVREPERHITAEMEKV-----VDIPCRAKGVPPPSI 343

  Fly    71 LWRKGSSVLTAGHLKITRDQRFKIVGDYNLQINGVKTQDAGDYICQLGDQENRDQVHTVEIL--V 133
            .|.|.::::..|  |:|   |||...|..|||:|:...|.|...|...:.....|..|...:  :
  Rat   344 TWYKDAALVEVG--KLT---RFKQRSDGGLQISGLLPDDTGMVQCFAHNAAGEAQTSTYLAVTSI 403

  Fly   134 PPTLRALPHNGQVTARKGSTVTLECKASGNPVPTIFWFKKD--VFSG------------------ 178
            .|.:...|.:.  |...|.:|.|.|:.||.|.|.|.|.|.:  :.||                  
  Rat   404 APNITRGPLDS--TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTLLESGSLLIS 466

  Fly   179 PTHLSDSSTLILENVDRHHAGTYQCSADN--GVKDRVSMDI----QLTILSPPEITVEKSWVHAS 237
            |||:||             ||||.|.|.|  || |..|.|:    :..|..||:   ::|.:   
  Rat   467 PTHISD-------------AGTYTCLATNSRGV-DEASADLVVWARTRITKPPQ---DQSVI--- 511

  Fly   238 EGYDVELVCIVHGD--VNSEMLWYQNSFLLDATDRRSMYPRDDRYSLIIRNFQPTDFGNYSCVAD 300
            :|....:||.|..|  |....:|.::...| |.:.......|...||.|......|.|.|:|...
  Rat   512 KGTQASMVCGVTHDPRVTVRYVWEKDGATL-AVETNPRIRLDRNGSLHISQTWSGDIGTYTCRVL 575

  Fly   301 NALGRTKKYIEVSGRPGPADFISPALSGFLDHYNLTWTIESIP-----PLDEIKLLYRRLLMNET 360
            :|.|.                         |..|....:..:|     |:..:..:.||.: |.|
  Rat   576 SAGGN-------------------------DSRNAHLRVRQLPHAPEHPVATLSTMERRAI-NLT 614

  Fly   361 YQHPGKWHEYHIKPTPIRTDGSHFLMSYLVKNLEHNAVYEAIV 403
            :..|              .||:..||.|:::..|:||.:..::
  Rat   615 WAKP--------------FDGNSPLMRYILEMSENNAPWTILL 643

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7166NP_001262181.1 IG_like 50..133 CDD:214653 21/84 (25%)
Ig 56..116 CDD:143165 17/59 (29%)
IG_like 144..221 CDD:214653 31/102 (30%)
IGc2 151..209 CDD:197706 25/79 (32%)
IG_like 232..313 CDD:214653 20/82 (24%)
Ig 242..311 CDD:143165 18/70 (26%)
Sdk2XP_006247755.1 IG_like 43..112 CDD:214653
IGc2 43..101 CDD:197706
IG_like 123..206 CDD:214653
Ig 135..191 CDD:299845
IG_like 225..307 CDD:214653 5/22 (23%)
IGc2 236..289 CDD:197706 1/4 (25%)
I-set 311..400 CDD:254352 24/98 (24%)
Ig 329..397 CDD:143165 19/72 (26%)
I-set 405..495 CDD:254352 33/105 (31%)
Ig 419..495 CDD:299845 30/89 (34%)
Ig 505..589 CDD:299845 23/115 (20%)
IG_like 505..589 CDD:214653 23/115 (20%)
FN3 593..684 CDD:238020 15/66 (23%)
FN3 696..789 CDD:238020
FN3 797..893 CDD:238020
FN3 898..986 CDD:238020
FN3 996..1090 CDD:238020
FN3 1102..1197 CDD:238020
FN3 1204..1293 CDD:238020
FN3 1304..1397 CDD:238020
FN3 1403..1487 CDD:238020
FN3 1506..1619 CDD:238020
FN3 1629..1722 CDD:238020
FN3 1727..1808 CDD:238020
FN3 1840..1919 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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