DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7166 and SIGLEC9

DIOPT Version :9

Sequence 1:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_006723209.1	Gene:	SIGLEC9 / 27180	HGNCID:	10878	Length:	481	Species:	Homo sapiens

Alignment Length:	284	Identity:	69/284 - (24%)
Similarity:	93/284 - (32%)	Gaps:	91/284 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 TRDQRFKIVGD-----YNLQINGVKTQDAGDYICQL-------GDQENRDQV------HTVEILV 133
            ||| ||.::||     ..|.|...:..|||.|..::       ..:.:|..|      |...||:
Human    87 TRD-RFHLLGDPHTKNCTLSIRDARRSDAGRYFFRMEKGSIKWNYKHHRLSVNVTALTHRPNILI 150

  Fly   134 PPTLRALPHNGQVTARKGSTVTLECKA-----SGNPVPTIFWFKKDVFSGPTHLSDSSTLILENV 193
            |.||.:           |....|.|..     .|.| |.|.|....|.......:.||.|.|...
Human   151 PGTLES-----------GCPQNLTCSVPWACEQGTP-PMISWIGTSVSPLDPSTTRSSVLTLIPQ 203

  Fly   194 DRHHAGTYQCSAD-NGVKDRVSMDIQLTILSPPE---ITV------------EKSWVHASEGYDV 242
            .:.|..:..|... .|.....:..:.|.:..||:   :||            ..|.:...||..:
Human   204 PQDHGTSLTCQVTFPGASVTTNKTVHLNVSYPPQNLTMTVFQGDGTVSTVLGNGSSLSLPEGQSL 268

  Fly   243 ELVCIVHGDVNSEMLWYQNSFLLDATDRRSMYPRDDRYSLIIRNF-----QPT------------ 290
            .|||.|                 ||.|  |..|.  |.||..|..     ||:
Human   269 RLVCAV-----------------DAVD--SNPPA--RLSLSWRGLTLCPSQPSNPGVLELPWVHL 312

  Fly   291 -DFGNYSCVADNALGRTKKYIEVS 313
             |...::|.|.|.||..:.|:.||
Human   313 RDAAEFTCRAQNPLGSQQVYLNVS 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	17/63 (27%)
		Ig	56..116	CDD:143165	13/33 (39%)
		IG_like	144..221	CDD:214653	17/82 (21%)
		IGc2	151..209	CDD:197706	15/63 (24%)
		IG_like	232..313	CDD:214653	25/98 (26%)
		Ig	242..311	CDD:143165	22/86 (26%)
SIGLEC9	XP_006723209.1	Ig_Siglec_N	23..140	CDD:143189	15/53 (28%)
		IG_like	26..>118	CDD:214653	12/31 (39%)
		Ig	151..222	CDD:299845	19/82 (23%)
		IG_like	258..336	CDD:214653	25/98 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910