DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7166 and LRIT1

DIOPT Version :9

Sequence 1:NP_001262181.1 Gene:CG7166 / 40401 FlyBaseID:FBgn0037107 Length:467 Species:Drosophila melanogaster
Sequence 2:NP_056428.1 Gene:LRIT1 / 26103 HGNCID:23404 Length:623 Species:Homo sapiens


Alignment Length:368 Identity:73/368 - (19%)
Similarity:115/368 - (31%) Gaps:126/368 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   142 HNGQVTARK--GSTVTLECKASGNPVPTIFWFKKD--VFSGPTHLSDSS-----TLI-LENVDRH 196
            |.|..:.|.  |.|..|.|.|:|.|.|.:.|.:.:  ..:|..|...||     ||: |..|...
Human   257 HPGVASIRSLLGGTALLRCGATGVPGPEMSWRRANGRPLNGTVHQEVSSDGTSWTLLGLPAVSHL 321

  Fly   197 HAGTYQCSADN--GVKDRVSMDIQLTILSPPEITVEKS-----WVHASEGYDVELVCIVHGDVNS 254
            .:|.|.|.|.|  |..:.|   |.|.:..||..|....     |.....|              .
Human   322 DSGDYICQAKNFLGASETV---ISLIVTEPPTSTEHSGSPGALWARTGGG--------------G 369

  Fly   255 EMLWYQNSFLLDATDRRSMYPR-----------DDRYSLIIRNFQPTDFGNYSCVADNALGRTKK 308
            |...|.|..:.....:   .|:           ..:..|.:.:||....|..|            
Human   370 EAAAYNNKLVARHVPQ---IPKPAVLATGPSVPSTKEELTLEHFQMDALGELS------------ 419

  Fly   309 YIEVSGRPGPAD---FISPALSGFLDH-YNLTWTIESIPPLDEIKLLY--------RRLLMNETY 361
                .||.||::   ..|..:.|...| .:|.|............:||        ||:::    
Human   420 ----DGRAGPSEARMVRSVKVVGDTYHSVSLVWKAPQAKNTTAFSVLYAVFGQHSMRRVIV---- 476

  Fly   362 QHPGKWHEYHIKPTPIRTDGSHFLMSYLVKNLEHNA--VYEAIVQAKNK---YGWNEISDIHQFY 421
             .|||        |.:...|       |:...::.|  ..:.:|..|.:   :..||:.|     
Human   477 -QPGK--------TRVTITG-------LLPKTKYVACVCVQGLVPRKEQCVIFSTNEVVD----- 520

  Fly   422 TRNHDLLLDIDMEYKMGISSNIRISPTVSGIILSAFILVLYPI 464
            ..|...|:::                    :::|..|::..|:
Human   521 AENTQQLINV--------------------VVISVAIVIALPL 543

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7166NP_001262181.1 IG_like 50..133 CDD:214653
Ig 56..116 CDD:143165
IG_like 144..221 CDD:214653 28/88 (32%)
IGc2 151..209 CDD:197706 22/67 (33%)
IG_like 232..313 CDD:214653 11/96 (11%)
Ig 242..311 CDD:143165 9/79 (11%)
LRIT1NP_056428.1 LRR 1 60..81
leucine-rich repeat 61..84 CDD:275378
LRR_8 63..143 CDD:290566
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378
LRR 3 108..129
LRR_8 131..202 CDD:290566
LRR_4 131..171 CDD:289563
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275378
LRR 5 156..177
leucine-rich repeat 157..180 CDD:275378
leucine-rich repeat 181..205 CDD:275378
TPKR_C2 201..>240 CDD:301599
Ig 267..345 CDD:299845 26/80 (33%)
IG_like 267..345 CDD:214653 26/80 (33%)
FN3 431..498 CDD:214495 16/86 (19%)
LRR 6. /evidence=ECO:0000305 571..594
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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