Protein Alignment CG7166 and NEGR1

DIOPT Version :9

• Sequence 1: NP_001262181.1
• Gene: CG7166 / 40401
• FlyBaseID: FBgn0037107
• Length: 467
• Species: Drosophila melanogaster
• Sequence 2: NP_776169.2
• Gene: NEGR1 / 257194
• HGNCID: 17302
• Length: 354
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 89/318 - (27%)
• Similarity: 132/318 - (41%)
• Gaps: 57/318 - (17%)

  Fly    53 GETIELPCKVQNLGSFVLLWRKGSSVLTAGHLKITRDQRFKI----VGDYNLQINGVKTQDAGDY 113
            |:|..|.|.::: |:....|...||::.||..|.:.|.|..|    ..||:|||..|...|.|.|
Human    53 GDTAVLRCYLED-GASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPY 116

  Fly   114 ICQLGDQE--NRDQVHTVEILVPPTLRALPHNGQVTARKGSTVTLECKASGNPVPTIFWFKKDVF 176
            .|.:..|.  ...||| :.:.|||.:..:  :..:|..:|:.|||.|.|:|.|.|:|.|
Human   117 TCSVQTQHTPRTMQVH-LTVQVPPKIYDI--SNDMTVNEGTNVTLTCLATGKPEPSISW------ 172

  Fly   177 SGPTHLSDSST-------LILENVDRHHAGTYQCSADNGVKDRVSMDIQLTILSPPEITVEKSWV 234
               .|:|.|:.       |.:..:.|..||.|:|||:|.|.......:::.:...|.|...||..
Human   173 ---RHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGT 234

  Fly   235 HASEGYDVELVCIVHGDVNSEMLWY---------QNSFLLDATDRRSMYPRDDRYSLIIRNFQPT 290
             .:.|....:.|...|.......||         |...::.....||:        |.:.|....
Human   235 -VTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSI--------LTVTNVTQE 290

  Fly   291 DFGNYSCVADNALGRTKKYIEVS-------GRPGPAD------FISPALSGFLDHYNL 335
            .||||:|||.|.||.|...:.::       |..|.||      ::...||.|...:.|
Human   291 HFGNYTCVAANKLGTTNASLPLNPPSTAQYGITGSADVLFSCWYLVLTLSSFTSIFYL 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	28/85 (33%)
		Ig	56..116	CDD:143165	21/63 (33%)
		IG_like	144..221	CDD:214653	25/83 (30%)
		IGc2	151..209	CDD:197706	23/64 (36%)
		IG_like	232..313	CDD:214653	22/89 (25%)
		Ig	242..311	CDD:143165	20/77 (26%)
NEGR1	NP_776169.2	IG	47..135	CDD:214652	28/83 (34%)
		IGc2	152..210	CDD:197706	23/66 (35%)
		Ig_3	225..301	CDD:372822	21/84 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810