DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7166 and Igsf9b

DIOPT Version :9

Sequence 1:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_011240777.1	Gene:	Igsf9b / 235086	MGIID:	2685354	Length:	1443	Species:	Mus musculus

Alignment Length:	379	Identity:	100/379 - (26%)
Similarity:	156/379 - (41%)	Gaps:	94/379 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 GGSFILPENDPPTTAPKFLSRGHLYKVIVGETIELPCKVQN--LGS---FVLLWRK-GSSV---L 79
            ||:..|.|.      |:|::      ...||.:.|.|.|.:  .|.   :|:.|.| |..:   :
Mouse    23 GGAHGLREE------PEFVT------ARAGEGVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFI 75

  Fly    80 TAG----HLKITRDQRFKIVGDYNLQINGVKTQDAGDYICQ--LGDQE-----NRDQVHTVEILV 133
            ..|    |:......|..:....:|::..|:::|.|.|.|:  :.||:     |...|| :.|..
Mouse    76 KFGYYPPHVDPEYAGRASLHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVH-LTINA 139

  Fly   134 PPTLRALPHNGQVTARKGSTVTLECKASGNPVPTIFWFKKDVFSGPT---HLSDSSTLILENVDR 195
            |||....|.. .:.|::|.::|:.|.|.|||.|.:.|.|:....|.:   .:||.| |.:.:|.|
Mouse   140 PPTFTETPPQ-YIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLGASAKYQVSDGS-LTVTSVSR 202

  Fly   196 HHAGTYQCSADNGVKDRVSMDIQLT-----ILSPPE-ITVEKSWVHASEGYDVELVCIVH---GD 251
            ...|.|.|.|.:...:.|.....|.     |:|||| |||..|       .|..|.|...   |:
Mouse   203 EDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNIS-------QDALLTCRAEAYPGN 260

  Fly   252 V------NSEMLWYQNS------FLLDATDRRSMYPRDDRYSLIIRNFQPTDFGNYSCVADNALG 304
            :      ..|.:::||.      .|:|.|             |||...:|.|.|.|:||..|:||
Mouse   261 LTYTWYWQDENVYFQNDLKLRVRILIDGT-------------LIIFRVKPEDAGKYTCVPSNSLG 312

  Fly   305 R--------TKKY-IEVSGRPGPADFISPALSGFLDHYNLTWTIESIPPLDEIK 349
            |        |.:| ..|...| |..::...:.|:     :...:::.||...:|
Mouse   313 RSPSASAYLTVQYPARVLNMP-PVIYVPVGIHGY-----IRCPVDAEPPATVVK 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	25/102 (25%)
		Ig	56..116	CDD:143165	16/72 (22%)
		IG_like	144..221	CDD:214653	24/84 (29%)
		IGc2	151..209	CDD:197706	21/60 (35%)
		IG_like	232..313	CDD:214653	26/104 (25%)
		Ig	242..311	CDD:143165	24/92 (26%)
Igsf9b	XP_011240777.1	Ig	43..117	CDD:319273	17/73 (23%)
		I-set	141..227	CDD:369462	26/87 (30%)
		Ig	231..323	CDD:386229	32/111 (29%)
		Ig	<355..416	CDD:386229	2/6 (33%)
		Ig	440..504	CDD:319273
		FN3	512..607	CDD:238020
		FN3	623..705	CDD:238020
		PHA03247	<900..1248	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810