DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7166 and Cilp

DIOPT Version :9

Sequence 1:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_775561.1	Gene:	Cilp / 214425	MGIID:	2444507	Length:	1250	Species:	Mus musculus

Alignment Length:	234	Identity:	61/234 - (26%)
Similarity:	94/234 - (40%)	Gaps:	58/234 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 IELPCKVQNLGSFVLLWRKGSSVLTAGHLKITRDQRFKIVG---DYNLQINGVKTQDAGDYICQL 117
            |.||......|:.|.|..|...:||    :.....||::.|   |....:...||:.|
Mouse   230 ISLPGGGPAPGAAVYLLAKAPKMLT----RTDSSGRFRVPGLCPDGKTILKITKTKFA------- 283

  Fly   118 GDQENRDQVHTVEILVPPT-----------LRA-LPH---NGQVTARK-GSTVTLECKASGNPVP 166
                      .:.|.:|.|           :|| .|:   |.::.||: |.:|:|.|||:|.|.|
Mouse   284 ----------PIMITMPKTSLKSATINAEFVRAETPYIVMNPEMKARRAGQSVSLCCKATGKPSP 338

  Fly   167 -TIFWFKKDVFSGPTHLSDSSTLILENVDRHHAGTYQCSADN---GVKDRVSMDIQLTILSPPEI 227
             ..||:..:....|:.....|.|:|.|:.:..||.|.|.|.:   .||.:|:   |||:::..|.
Mouse   339 DKYFWYHNNTLLDPSLYKHESKLVLRNLQQDQAGEYFCKAQSDAGAVKSKVT---QLTVIAHDET 400

  Fly   228 TVEKSWVHASEGYDVELVCIVHGDVNSEMLWYQNSFLLD 266
            ....:    .|.|   |:.:.|....:.    .|||..|
Mouse   401 PCNPT----PESY---LIRLPHDCFQNA----SNSFYYD 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	17/79 (22%)
		Ig	56..116	CDD:143165	16/62 (26%)
		IG_like	144..221	CDD:214653	28/81 (35%)
		IGc2	151..209	CDD:197706	21/61 (34%)
		IG_like	232..313	CDD:214653	8/35 (23%)
		Ig	242..311	CDD:143165	6/25 (24%)
Cilp	NP_775561.1	Mucin2_WxxW	55..139	CDD:290069
		TSP1	152..200	CDD:214559
		IG_like	321..394	CDD:214653	26/75 (35%)
		IGc2	323..383	CDD:197706	21/59 (36%)
		CarbopepD_reg_2	492..580	CDD:290434
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7834
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950