DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7166 and zig-3

DIOPT Version :9

Sequence 1:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_509336.1	Gene:	zig-3 / 192088	WormBaseID:	WBGene00006980	Length:	251	Species:	Caenorhabditis elegans

Alignment Length:	225	Identity:	56/225 - (24%)
Similarity:	88/225 - (39%)	Gaps:	45/225 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 QVHTVEILVPPTLRALPHNGQVTARKGSTVTLECKASGNPVPTIFWFKK----------DVFS-- 177
            ::.:..:...|:|:.:......|...|.:|||.|.....|...|:|.|.          :||.
Worm    32 EIDSTHLTTKPSLKIIEGLEDNTVSTGESVTLRCDVLSTPTGVIYWEKDGQRIQGDKELNVFEKV 96

  Fly   178 ----GPTHLSD--SSTLILENVDRHHAGTYQCSADNGVKDRVSMDIQLTI-----------LSPP 225
                |||..|.  :|:..:...:.||.|:|:|.|.|| .|.|....::::           .|.|
Worm    97 LNAMGPTVESGIITSSYQIPCANLHHIGSYKCVATNG-HDTVESSAKISVEGQTVKCKSTRRSAP 160

  Fly   226 EITVEKSWVHASEGYDVELVCIVHGDVNSEMLWYQNSFLLD-ATDRRSMYPRDDRYSLIIRNFQP 289
            .||:........:.....|:|  ..|..:...|......:| .:.|..:.|..|   |:||..|.
Worm   161 VITMSTESRFELQDNAATLIC--RADRRANWNWMFEDKKIDFDSGRYELLPSGD---LLIRKIQW 220

  Fly   290 TDFGNYSCVADNALGR---------TKKYI 310
            :|.|:|.|:|.|..|.         |||:|
Worm   221 SDMGSYFCIAHNKYGESRGETFLYPTKKHI 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	0/7 (0%)
		Ig	56..116	CDD:143165
		IG_like	144..221	CDD:214653	27/94 (29%)
		IGc2	151..209	CDD:197706	23/75 (31%)
		IG_like	232..313	CDD:214653	23/89 (26%)
		Ig	242..311	CDD:143165	23/79 (29%)
zig-3	NP_509336.1	I-set	45..145	CDD:254352	27/100 (27%)
		Ig	61..142	CDD:143165	25/81 (31%)
		IG_like	177..244	CDD:214653	19/71 (27%)
		Ig	<191..237	CDD:299845	16/48 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810