DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7166 and zig-4

DIOPT Version :9

Sequence 1:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_509335.1	Gene:	zig-4 / 181051	WormBaseID:	WBGene00006981	Length:	253	Species:	Caenorhabditis elegans

Alignment Length:	211	Identity:	48/211 - (22%)
Similarity:	78/211 - (36%)	Gaps:	47/211 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 VEILVPPTLRALPHNGQVTARKGSTVTLECKASGNPVPTIFW-FKKDVFSGPTHLS--------- 183
            ::|:.|.....:|        .|.|..|.|.....|..||.| |...:..|...|:
Worm    46 IKIVAPLESALIP--------GGETYQLRCDIMSTPAATIHWKFNGKLIQGSNELNVEEKLLNFG 102

  Fly   184 --------DSSTLILENVDRHHAGTYQCSADNG---VKDRVSMDIQ-------LTILSPPEITVE 230
                    .:|.|.::.....::|||.|...||   ::....::|:       ....|.|||..
Worm   103 KAIVDTGIVASILTIQCPSAENSGTYSCVGYNGHQTIETVAEVEIEGEASGCRSNHKSAPEIVF- 166

  Fly   231 KSWVHA---SEGYDVELVCIVHGDVNSEMLWYQNSFLLDATDRRSMYPRDDRYSLIIRNFQPTDF 292
              |..:   ..|....|||..:..|  :.:|..|..|:...|:.::....|   |:|:|....|.
Worm   167 --WTDSRFEMTGNVATLVCRANQQV--DWVWMSNDELVKNNDKFTVLSNGD---LVIKNIVWDDM 224

  Fly   293 GNYSCVADNALGRTKK 308
            |.|:|:|.|..|..::
Worm   225 GTYTCIARNQFGEARQ 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	1/3 (33%)
		Ig	56..116	CDD:143165
		IG_like	144..221	CDD:214653	20/104 (19%)
		IGc2	151..209	CDD:197706	19/78 (24%)
		IG_like	232..313	CDD:214653	21/80 (26%)
		Ig	242..311	CDD:143165	19/67 (28%)
zig-4	NP_509335.1	I-set	47..147	CDD:254352	22/107 (21%)
		Ig	65..144	CDD:143165	17/78 (22%)
		IG_like	176..245	CDD:214653	20/70 (29%)
		Ig	<193..238	CDD:299845	15/47 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810