DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7166 and rig-3

DIOPT Version :9

Sequence 1:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_509155.1	Gene:	rig-3 / 180958	WormBaseID:	WBGene00004370	Length:	487	Species:	Caenorhabditis elegans

Alignment Length:	439	Identity:	92/439 - (20%)
Similarity:	162/439 - (36%)	Gaps:	120/439 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 VLLWRKGSSVLTAGHLKITRDQRFKIVGDYNLQINGVKTQDAGDYIC--QLGDQENRDQVHTVEI 131
            |:|..|||.     |.|.            :|..:.|.|:|.|.|.|  :....||.::  |:::
Worm    95 VILNEKGSK-----HRKT------------SLHFSSVHTRDTGLYTCTGRTAGGENFEK--TIKL 140

  Fly   132 LVPPTLRALPHNGQVT---ARKGSTVTLEC---------------KASGNPVPTIFWFKKDVFSG 178
            :|.|   |:..|.:.|   |..|..:|::|               ..:|.|:....|
Worm   141 VVLP---AIEWNDKDTVKGALLGEPITIDCGVKGPSGKEPMIQMTNGNGEPLDEEIW-------- 194

  Fly   179 PTHLSDSSTLILENVDRHHAG-TYQC----------SADNGVKDRVSMDIQLTILSPPEITVEKS 232
             |...:.:|  ::::.:.||. |..|          ..:..|.||  .|:.:.:.:.||...|:|
Worm   195 -TIAGNEAT--IDSLKKEHAELTVSCITIEMHQETSKEEFPVVDR--KDVNIEVYTLPEFETEES 254

  Fly   233 ---WVHASEGYDVELVCIV-------------HGDVNSEMLWYQNSFLLDATDRRSMYPRDDRYS 281
               .|..:...|..:.|.|             |||...:|....|.|:.....:.:        .
Worm   255 VQYTVIDNHVRDAIIYCNVTHSFPPVRHYTFYHGDEEIKMSDKFNIFVNVGVSQGA--------H 311

  Fly   282 LIIRNFQPTDFGNYSCVADNALGRTKKYIEVSGRPGPADFISPALSGFLD-HYNLTWTIESIP-- 343
            |.|.|....|.|.|.|.|:|...::...|.:.....||:   |.::...| .:::.|.:|||.
Worm   312 LKIHNVNENDLGTYKCEANNIKAKSYHTIHLREANAPAE---PKVTLIEDKRHSIIWKVESIDRD 373

  Fly   344 ---PLDEIKLLYRRLLMNETYQHPG---------KWHEYHI-KPTPIRTDGSHFLMSYLVKNLEH 395
               |:..:::   |.|...|.:..|         .|..:.| ....|:.||     .|.:..|.|
Worm   374 PDLPMTAVEI---RHLRAGTAEASGVSDEDISDAYWKSHSIFMQRNIKDDG-----IYEINGLRH 430

  Fly   396 NAVYEAIVQAKNKYGWNEISDIHQFYTRNHDL-LLD--IDMEYKMGISS 441
            ...|....:..|:.|:.:...:......:||| ::|  .|.::.:.:::
Worm   431 GHEYVWRFRQINEAGFGDSVVLRAKTLDDHDLEMMDSASDSKFPLALAT 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	17/65 (26%)
		Ig	56..116	CDD:143165	14/48 (29%)
		IG_like	144..221	CDD:214653	18/105 (17%)
		IGc2	151..209	CDD:197706	12/83 (14%)
		IG_like	232..313	CDD:214653	21/96 (22%)
		Ig	242..311	CDD:143165	17/81 (21%)
rig-3	NP_509155.1	IG_like	48..142	CDD:214653	17/65 (26%)
rig-3	NP_509155.1	Ig	267..341	CDD:319273	17/81 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900