DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7166 and Ncam1

DIOPT Version :9

Sequence 1:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_006510118.1	Gene:	Ncam1 / 17967	MGIID:	97281	Length:	1162	Species:	Mus musculus

Alignment Length:	323	Identity:	91/323 - (28%)
Similarity:	142/323 - (43%)	Gaps:	64/323 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 GETIELPCKVQNLGSFVLLWR-KGSSVLTAGHLKITRDQRFKIVGDYNLQINGVKTQDAGDYICQ 116
            ||...:.|.|.:.....::|: ||..|:      :.:|.||.::.:..|||.|:|..|.|.|.|:
Mouse   132 GEDAVIVCDVVSSLPPTIIWKHKGRDVI------LKKDVRFIVLSNNYLQIRGIKKTDEGTYRCE 190

  Fly   117 LGDQENRDQVH----TVEILVPPTLRALPHNGQVTARKGSTVTLECKASGNPVPTIFWFK----- 172
             |....|.:::    .|.:.||||::|.......||..|.:|||.|.|.|.|.||:.|.|
Mouse   191 -GRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPI 254

  Fly   173 --------KDVFSGPTHLSDSSTLILENVDRHHAGTYQCSADN--GVKDRVSMDIQLTILSPPEI 227
                    |.:||     .|||.|.:.|||::....|.|.|:|  |.:|   ..|.|.:.:.|:|
Mouse   255 ENEEEDDEKHIFS-----DDSSELTIRNVDKNDEAEYVCIAENKAGEQD---ASIHLKVFAKPKI 311

  Fly   228 TVEKSWVHASEGYDVELVCIVHGDVNSEMLWYQNSFLLDATDRRSMYPRDDRY------------ 280
            |..::.........|.|.|...||....:.|..::..:.:.::.| :.|.::.
Mouse   312 TYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKAS-WTRPEKQETLDGHMVVRSH 375

  Fly   281 ----SLIIRNFQPTDFGNYSCVADNALGRTKK--YIEVSGRPGPADFISPALSGFLDHYNLTW 337
                ||.:::.|.||.|.|.|.|.|.:|:..:  |:||.        .:|.|.|.:..|  ||
Mouse   376 ARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQ--------YAPKLQGPVAVY--TW 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	23/84 (27%)
		Ig	56..116	CDD:143165	17/60 (28%)
		IG_like	144..221	CDD:214653	32/91 (35%)
		IGc2	151..209	CDD:197706	26/72 (36%)
		IG_like	232..313	CDD:214653	21/98 (21%)
		Ig	242..311	CDD:143165	20/86 (23%)
Ncam1	XP_006510118.1	Ig1_NCAM-1	20..115	CDD:143273
		IG	124..190	CDD:214652	19/63 (30%)
		Ig3_NCAM-1_like	211..308	CDD:143207	36/104 (35%)
		Ig_NCAM-1	307..413	CDD:143277	23/106 (22%)
		Ig_3	417..494	CDD:372822	6/14 (43%)
		FN3	509..606	CDD:238020
		fn3	649..731	CDD:365830
		PHA03247	<905..1140	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900