DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7166 and negr1

DIOPT Version :9

Sequence 1:NP_001262181.1 Gene:CG7166 / 40401 FlyBaseID:FBgn0037107 Length:467 Species:Drosophila melanogaster
Sequence 2:XP_031755650.1 Gene:negr1 / 100127726 XenbaseID:XB-GENE-987949 Length:388 Species:Xenopus tropicalis


Alignment Length:305 Identity:81/305 - (26%)
Similarity:134/305 - (43%) Gaps:46/305 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    53 GETIELPCKVQNLGSFVLLWRKGSSVLTAGHLKITRDQRFKIV----GDYNLQINGVKTQDAGDY 113
            |||..|.|.::. |:....|...||::.||..|.:.|.|..|.    .:|:|:|..|...|.|.|
 Frog    54 GETAMLRCFLEE-GASKGAWLNRSSIIFAGGDKWSVDPRVSIATSSKQEYSLRIQKVDVSDDGPY 117

  Fly   114 ICQLGDQENRD--QVHTVEILVPPTLRALPHNGQVTARKGSTVTLECKASGNPVPTIFWFKKDVF 176
            .|.:..:.:..  ||| :.:.|.|.:..:  :..:|..:|:.|:|.|.|:|.|.|:|.|      
 Frog   118 TCSVQTEHSPRTLQVH-LTV
HVSPKIYDI--SSDMTVNEGTNVSLICLATGKPEPSISW------ 173

  Fly   177 SGPTHLSDSST-------LILENVDRHHAGTYQCSADNGV------KDRVSMDIQLTIL--SPPE 226
               .|:|.|:.       |.:..:.|..||.|:|||:|.|      |.:|:::...|||  :|..
 Frog   174 ---RHISPSAKQFGSGQYLDIYGITRDQAGDYECSAENDVSFPDVKKVKVTVNFAPTILEITPTG 235

  Fly   227 ITVEKSWVHASEGYDVELVCIVHGDVNSEMLWYQNSFLLDATDRR-SMYPRDDRYSLIIRNFQPT 290
            :::.::.:...|      ...|...|   ..||:....|....|. .:...:.|..|.:.|....
 Frog   236 VSLGRTGLIRCE------TAAVPAPV---FEWYKGEKKLTNGQRGIRIQNYNTRSILTVSNVTEE 291

  Fly   291 DFGNYSCVADNALGRTKKYIEVSG--RPGPADFISPALSGFLDHY 333
            .||||:|||.|.||.:...:.::.  .|.....::.:....:.||
 Frog   292 HFGNYTCVAVNKLGTSNASLPLNQIIEPSTTSPVTSSAKYSVKHY 336

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7166NP_001262181.1 IG_like 50..133 CDD:214653 26/85 (31%)
Ig 56..116 CDD:143165 19/63 (30%)
IG_like 144..221 CDD:214653 26/89 (29%)
IGc2 151..209 CDD:197706 22/64 (34%)
IG_like 232..313 CDD:214653 20/81 (25%)
Ig 242..311 CDD:143165 19/69 (28%)
negr1XP_031755650.1 Ig 44..136 CDD:416386 26/83 (31%)
FR1 44..62 CDD:409353 4/7 (57%)
Ig strand A' 47..53 CDD:409353
Ig strand B 55..63 CDD:409353 4/7 (57%)
CDR1 63..68 CDD:409353 1/5 (20%)
FR2 69..75 CDD:409353 1/5 (20%)
Ig strand C 69..74 CDD:409353 1/4 (25%)
CDR2 76..87 CDD:409353 5/10 (50%)
Ig strand C' 78..82 CDD:409353 0/3 (0%)
Ig strand C' 84..87 CDD:409353 1/2 (50%)
FR3 88..122 CDD:409353 11/33 (33%)
Ig strand D 91..98 CDD:409353 2/6 (33%)
Ig strand E 101..107 CDD:409353 2/5 (40%)
Ig strand F 114..122 CDD:409353 3/7 (43%)
CDR3 123..127 CDD:409353 0/3 (0%)
Ig strand G 127..136 CDD:409353 3/9 (33%)
FR4 129..136 CDD:409353 3/7 (43%)
Ig_3 140..208 CDD:404760 23/78 (29%)
Ig strand A' 146..151 CDD:409353 0/4 (0%)
Ig strand B 157..164 CDD:409353 3/6 (50%)
Ig strand C 170..175 CDD:409353 2/13 (15%)
Ig strand C' 177..179 CDD:409353 1/1 (100%)
Ig strand E 187..193 CDD:409353 1/5 (20%)
Ig strand F 200..207 CDD:409353 4/6 (67%)
Ig strand G 214..222 CDD:409353 2/7 (29%)
Ig_3 226..302 CDD:404760 21/84 (25%)
putative Ig strand A 226..232 CDD:409353 3/5 (60%)
Ig strand B 242..246 CDD:409353 0/3 (0%)
Ig strand C 255..259 CDD:409353 1/6 (17%)
Ig strand E 281..285 CDD:409353 1/3 (33%)
Ig strand F 295..300 CDD:409353 3/4 (75%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X97
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
22.000

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