Protein Alignment S1P and Fur2

DIOPT Version :10

• Sequence 1: NP_649337.2
• Gene: S1P / 40399
• FlyBaseID: FBgn0037105
• Length: 1012
• Species: Drosophila melanogaster
• Sequence 2: XP_061499326.1
• Gene: Fur2 / 1273048
• VectorBaseID: AGAMI1_010899
• Length: 1513
• Species: Anopheles gambiae
• Alignment Length: 691
• Identity: 144/691 - (20%)
• Similarity: 212/691 - (30%)
• Gaps: 269/691 - (38%)

  Fly   154 WKLGITGKGVKVAIFDTGLTKNHPHF----------------RNVKERTNWTNEKSLDDRVSHGT 202
            |:.|.|||||.|:|.|.|:.:|||..                .:...|.|..|:        |||
Mosquito   273 WQKGYTGKGVVVSILDDGIQRNHPDLALNYDPAASYDINGNDSDPMPRDNGDNK--------HGT 329

  Fly   203 FVAGVIASSRECLGFAPDADLYIFKVFTNSQVSYTSWFLDAFNYAIYRKINILNLSIGGPDFMD- 266
            ..||.:|:             ..|..:....|:|                   |.||||...:|
Mosquito   330 RCAGEVAA-------------VAFNQYCGVGVAY-------------------NASIGGVRMLDG 362

  Fly   267 --SPFVE-KVLELSANNVIMISAAGN--------DGP--------LYGTLN-------------- 298
              :..|| |.|.|..:::.:.||:..        |||        ::|..:
Mosquito   363 TVNDAVEAKALGLYPDHIDIYSASWGPEDDGSTVDGPGPLARRAFIFGVTSGRQGKGSIFIWASG 427

  Fly   299 NPGDQSDVVGVGGIQ---FDDKIAKFSSRGMTTWELPLGYGRMGLDIVTYGSQVEGSDV------ 354
            |.|..:|.....|..   |...|:..:..|...|.|......:.   .||.|...|.|.
Mosquito   428 NGGRYTDSCNCDGYTNSIFTLSISSATQGGYKPWYLEECSSTLA---TTYSSGTPGHDKSVATVD 489

  Fly   355 RKGCRR--------LSGTSVSSPVVAGAAALLISGAFQKIDYINPASLKQVLIEGAEKLPHYNMF 411
            ..|..|        .:|||.|:|:.||.|||.:..        |||.
Mosquito   490 MDGSLRPDRICTVEHTGTSASAPLAAGIAALALEA--------NPAL------------------ 528

  Fly   412 EQGAGKLNLLKSMQLLLSYKPKITLIPAYLDFTQNYMWPYSSQPLYYGSSVAIANVTILNGIS-V 475
                    ..:.||.|:       ::.:..|       |...:|.:           ||||:. .
Mosquito   529 --------TWRDMQYLV-------VLTSRSD-------PLEKEPGW-----------ILNGVKRK 560

  Fly   476 TSHIVGIPKWIPDFENQGQFLQVSAQVSPIVWPWTGWMSVFIAVKKEGENFEGVCKGSITLVLES 540
            .||..|.           ..:...|.|| :...||...|..|...:| .|.:...:.|:...|::
Mosquito   561 VSHKFGY-----------GLMDAGAMVS-LAEQWTTVPSQHICKSRE-INEDRPIEVSVGYTLQT 612

  Fly   541 FKQ------TTNETHVTE-VDFPLTIKVTPKPPRNKRILWDQYHSLRYPPRYI-------PRDDL 591
            ...      |.||....| |...:|::..|:  .|.|||      |..|....       |||..
Mosquito   613 HMDVNGCAGTVNEVRFLEHVQCKITLRFFPR--GNLRIL------LTSPMGTTSTLLFERPRDIT 669

  Fly   592 KVKLDPLDWRADHIHTNFRDMYTHLRNVGYYIDVLREPFTCFNASDYGALLIVDPERGFGD---E 653
            |...|  ||                            ||  .:...:|       ||..|.   :
Mosquito   670 KSNFD--DW----------------------------PF--LSVHFWG-------ERAEGRWTLQ 695

  Fly   654 EINALQENVYKRGL----NVVVFGDWYNTTVMKKIKFFDENTRQWWTPDTGGAN---IPALNDLL 711
            .:|.....|.:.|:    .::.:|     |....|:...|.||...:....|.|   .|...||.
Mosquito   696 ILNGGPRRVSQPGILSKWQLIFYG-----TQTNPIRLKSEGTRTAGSAGYSGLNPFVFPTETDLN 755

  Fly   712 KPFGIAFGDFVGEGHFKLGD--------HSMYYASGATIVK 744
            :..|...|  .|.|:::..|        .:::..:|:.|.|
Mosquito   756 QQAGALGG--AGAGYYQSADLYSNFMNYPNLFSGAGSGIDK 794

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S1P	NP_649337.2	Peptidases_S8_SKI-1_like	154..407	CDD:173805	72/319 (23%)
		DUF4350	610..754	CDD:464118	28/153 (18%)
Fur2	XP_061499326.1	None