Protein Alignment S1P and pcsk7

DIOPT Version :10

• Sequence 1: NP_649337.2
• Gene: S1P / 40399
• FlyBaseID: FBgn0037105
• Length: 1012
• Species: Drosophila melanogaster
• Sequence 2: NP_001307357.2
• Gene: pcsk7 / 100009656
• ZFINID: ZDB-GENE-030131-7293
• Length: 709
• Species: Danio rerio
• Alignment Length: 656
• Identity: 134/656 - (20%)
• Similarity: 225/656 - (34%)
• Gaps: 233/656 - (35%)

  Fly    93 LQTHPSV----KAVVPQRSVRRI-LNYDAYSNLTYIHRHPQGVLRNRNPNNDRHRQLCSVLHANI 152
            |..||.|    :..|.:||.|.: .|...:.:..::|             ||..|.:  .::...
Zfish    92 LDRHPHVAWHSQENVLRRSKRSVHFNDPKFPSQWHLH-------------NDMKRGM--DINVTG 141

  Fly   153 LWKLGITGKGVKVAIFDTGLTKNHPHFRNVKERTNWTNEKSLD------------DRVS---HGT 202
            :|:..|||.||.|.:.|.|:..|....     :.|::.|.|.|            |..|   |||
Zfish   142 VWERNITGAGVTVVVVDDGIQHNLADI-----QPNYSPEGSYDLNSNDPDPMPHPDGPSDNHHGT 201

  Fly   203 FVAGVIA----SSRECLGFAPDADLYIFKV----FTNSQVSYTSWFLDAFNYAIYRKINILNLSI 259
            ..||.||    :|...:|.|..:.:...:|    .|:|        ::|..:..:.::|.:....
Zfish   202 RCAGEIAAVSNNSFCAVGVAYGSRVAGIRVLDGPLTDS--------MEAIAFNKHYQVNDIYSCS 258

  Fly   260 GGPD----FMDSPFVEKVLELSANNV--------IMISAAGNDGPLYGTLNNPGDQSDV--VGVG 310
            .|||    .:|.|.......|....:        |.|.|:||.|......|..|..:.:  |.:|
Zfish   259 WGPDDDGRTVDGPHPLGKAALQHGVIAGRKGFGSIFIVASGNGGQNQDNCNYDGYANSIYTVTIG 323

  Fly   311 GI-------QFDDKIAK-----FSS-----RGMTT--WELPLGYGRMGLDIVTYGSQVEGSDVRK 356
            .:       .:.::.|.     |||     |.:.|  |.|..|.|      .|.|.
Zfish   324 AVDESGRKPSYAEECASMLAVTFSSGNTPLRSIVTSDWSLQSGTG------CTSGH--------- 373

  Fly   357 GCRRLSGTSVSSPVVAGAAALLISG----AFQKIDYINPASLKQ------VLIEGAEKLPHYNMF 411
                 :|||.::|:.||..||::..    :::.:.:|...:..|      .:..||   ..::..
Zfish   374 -----TGTSAAAPLAAGMVALMLQVRPCLSWRDVQHIITYTATQHDLQADWVTNGA---GFHHSH 430

  Fly   412 EQGAGKLN---------LLKSMQLLLSYKPKI----TLIPAYLDFTQNYMWPYSSQPLYYGSSVA 463
            :.|.|.||         :.:|:..|:||:..:    .:|....:.||.  |..|...|.......
Zfish   431 KYGFGLLNAWRLVNAAKVWESVPFLVSYQSPVLRVNEVITTSTNLTQT--WNVSESDLQRSGMQT 493

  Fly   464 IANVTILNGI---------------SVTSHIVGIPKWIPDFENQGQFLQVSAQVSPIVWPWTGWM 513
            :.:|::...|               |..|.::|..:.: |.::.|            :..||
Zfish   494 LEHVSVTLSIQHPRRGNLQILLLCPSGISSLIGARRAL-DVDSAG------------LTDWT--- 542

  Fly   514 SVFIAVKKEGENFEGVCKGSITL---------VLESFK-----------QTTNETHVTE------ 552
              |..|:..||..||  :.|:.:         :|:|:|           |.|:...|.|
Zfish   543 --FSTVRCWGERAEG--QYSLLIMDDAPLSSGILKSWKLTLYGSSLSHQQVTDRQRVVEEAMSGH 603

  Fly   553 -------------VDFPLTIKVTPKPPRNKR---------ILWDQYHSLRYPPRYIPRDDLKVKL 595
                         :|.|..| |.|....:.:         :.|..|::            |:|.|
Zfish   604 YLSSSFSLPCPPGIDVPAEI-VNPFTSSSLKSLLLLGCFALFWSLYYT------------LEVAL 655

  Fly   596 DPLDWR 601
            ...|||
Zfish   656 THWDWR 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S1P	NP_649337.2	Peptidases_S8_SKI-1_like	154..407	CDD:173805	71/318 (22%)
		DUF4350	610..754	CDD:464118
pcsk7	NP_001307357.2	None