Protein Alignment TfAP-2 and tfap2e

DIOPT Version :9

• Sequence 1: NP_001262178.1
• Gene: TfAP-2 / 40398
• FlyBaseID: FBgn0261953
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: XP_021323693.1
• Gene: tfap2e / 393794
• ZFINID: ZDB-GENE-040426-1455
• Length: 432
• Species: Danio rerio
• Alignment Length: 467
• Identity: 214/467 - (45%)
• Similarity: 271/467 - (58%)
• Gaps: 81/467 - (17%)

  Fly    29 GLSSGSAAYTTHSGGHTGRSGPATGHSGHSSTHGSAATMHHQSLQSDFQPPYFPPPFHHSTQSPP 93
            ||||.|      .||...:....     :.:.:.||..:.| :..|||||||||||:..|:.|..
Zfish    20 GLSSSS------PGGRLSQLSQL-----NQAAYSSAPPLCH-TPASDFQPPYFPPPYPQSSLSYS 72

  Fly    94 QQQISGYLQNHGALEYLGTDPY-GQPLSSLHHAPLHHYNQLA--GLRSTQDQLG-IHRTHR---- 150
            |.|..||             |: .:|..||:  .||.:.|.|  ..||..:..| :.:.||
Zfish    73 QSQDGGY-------------PHLPEPYPSLN--SLHQHQQAAWHSQRSRSEDAGLLSQPHRALSL 122

  Fly   151 --EAELQGHVTQLSHGFPYTDRRSDYGSAISAGAAHGTRLGHEHESLALHQALQNAVDDVQ---- 209
              ..|..|....|:||.      .|..:|:..|            .|.:| |:.:.:||:|
Zfish   123 DPRREYPGVPRLLTHGL------GDGAAALGDG------------PLGMH-AVHHGLDDIQGLEE 168

  Fly   210 APA---LDDNVAFMSDLP------LIKSMKSGKEAGNIGS-GSPSEVFCAVPGRLSLLSSTSKYK 264
            |.|   ||.:|.....||      .|.::...||...:|. .:|:||||:|||||||||||||||
Zfish   169 ASALGILDHSVIKKVPLPSKLNGSTISALSLSKEGLGLGGVSNPAEVFCSVPGRLSLLSSTSKYK 233

  Fly   265 VTIAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRLLREKLEKIGLNLPAGRRKAANVTLLTSLV 329
            ||:.||||||:||||||||||||||||||||||||.|||:||||||||||||||||||||||:||
Zfish   234 VTVGEVQRRLAPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTALV 298

  Fly   330 EGEATHLAKDFHFVCETEFPARQLAEYIVRHQTEPQDSYRRKELILHSQQITKELMQILSQDRTT 394
            ||||.|||:||.:|||||||||..|||:.| ||||.....|:.::|.:::|.||.:.::||||:.
Zfish   299 EGEAVHLARDFGYVCETEFPARATAEYLCR-QTEPDQLPTRRSMLLATKEICKEFVDLMSQDRSP 362

  Fly   395 HFGTRSQHLLEPSMQRHLTHFSLITHGFGSPAIMAVLHAFQTFLNESLNYLEKLYPSNGGGMVSS 459
            ...:|....|||.:|..||||||:|||||:||:.|.|.|||::|.|:|..|:|  ..|||
Zfish   363 LGASRPTPCLEPGVQSSLTHFSLLTHGFGTPALCAALSAFQSYLLEALKLLDK--GENGG----- 420

  Fly   460 SLDKSKIDNEKK 471
               |:..|.|.|
Zfish   421 ---KNHHDKELK 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfAP-2	NP_001262178.1	TF_AP-2	247..441	CDD:397406	135/193 (70%)
tfap2e	XP_021323693.1	TF_AP-2	216..409	CDD:308749	135/193 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596532
Domainoid	1	1.000	278	1.000	Domainoid score	I1679
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	325	1.000	Inparanoid score	I2463
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D287275at33208
OrthoFinder	1	1.000	-	-		FOG0000991
OrthoInspector	1	1.000	-	-		otm26176
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10812
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10438
SonicParanoid	1	1.000	-	-		X400
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	11.030