Protein Alignment TfAP-2 and Tfap2a

DIOPT Version :9

• Sequence 1: NP_001262178.1
• Gene: TfAP-2 / 40398
• FlyBaseID: FBgn0261953
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: XP_038951615.1
• Gene: Tfap2a / 306862
• RGDID: 1310267
• Length: 439
• Species: Rattus norvegicus
• Alignment Length: 449
• Identity: 211/449 - (46%)
• Similarity: 271/449 - (60%)
• Gaps: 49/449 - (10%)

  Fly    40 HSGGHTGRSG-PATGHSGHSSTHGSAATMHHQSLQSDFQPPYFPPPFHHSTQSPPQQQISGYLQN 103
            |.|...|.:. |..|..| .|.:.||..:.| :..:||||||||||:         |.|  |.|:
  Rat    20 HDGTSNGTARLPQLGTVG-QSPYTSAPPLSH-TPNADFQPPYFPPPY---------QPI--YPQS 71

  Fly   104 HGALEYLGTDPYGQPLSSLHHAPLHHYNQLAGLRSTQDQLGIHRTHREAELQGHVTQLSHGFPYT 168
            .....:: .|||.  |:.||..|...:....|.|.:|:. |:..|||         .|.|.....
  Rat    72 QDPYSHV-NDPYS--LNPLHAQPQPQHPGWPGQRQSQES-GLLHTHR---------GLPHQLSGL 123

  Fly   169 DRRSDYGSAISAGAAHGTR-LGHEHESLALHQALQNAVDDVQAPALDDNVAFMSDLPLIKS---- 228
            |.|.||..  .....||.. ||.....|.:| :|.:|::||  |.::|....:.|..:||.
  Rat   124 DPRRDYRR--HEDLLHGPHGLGSGLGDLPIH-SLPHAIEDV--PHVEDPGINIPDQTVIKKGPVS 183

  Fly   229 -MKSGKEA--------GNIGSG--SPSEVFCAVPGRLSLLSSTSKYKVTIAEVQRRLSPPECLNA 282
             .||...|        .|:..|  :|:||||:|||||||||||||||||:|||||||||||||||
  Rat   184 LSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNA 248

  Fly   283 SLLGGVLRRAKSKNGGRLLREKLEKIGLNLPAGRRKAANVTLLTSLVEGEATHLAKDFHFVCETE 347
            |||||||||||||||||.|||||:|||||||||||||||||||||||||||.|||:||.:|||||
  Rat   249 SLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETE 313

  Fly   348 FPARQLAEYIVRHQTEPQDSYRRKELILHSQQITKELMQILSQDRTTHFGTRSQHLLEPSMQRHL 412
            |||:.:||::.|..::|.:...||.::|.::||.||...:|:|||:....:|...:|||.:|..|
  Rat   314 FPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCL 378

  Fly   413 THFSLITHGFGSPAIMAVLHAFQTFLNESLNYLEKLYPSNGGGMVSSSLDKSKIDNEKK 471
            |||:||:|||||||:.|.:.|.|.:|.|:|..::|:|.||.....:.:..||. |.|:|
  Rat   379 THFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNSHTDNSAKSS-DKEEK 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfAP-2	NP_001262178.1	TF_AP-2	247..441	CDD:397406	133/193 (69%)
Tfap2a	XP_038951615.1	TF_AP-2	213..407	CDD:397406	133/193 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354257
Domainoid	1	1.000	277	1.000	Domainoid score	I1652
eggNOG	1	0.900	-	-		E1_KOG3811
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2421
Inparanoid	1	1.050	321	1.000	Inparanoid score	I2431
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D287275at33208
OrthoFinder	1	1.000	-	-		FOG0000991
OrthoInspector	1	1.000	-	-		otm45027
orthoMCL	1	0.900	-	-		OOG6_105211
Panther	1	1.100	-	-	O	PTHR10812
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X400
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.800