Protein Alignment TfAP-2 and Tfap2d

DIOPT Version :9

• Sequence 1: NP_001262178.1
• Gene: TfAP-2 / 40398
• FlyBaseID: FBgn0261953
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_001366002.1
• Gene: Tfap2d / 226896
• MGIID: 2153466
• Length: 456
• Species: Mus musculus
• Alignment Length: 474
• Identity: 201/474 - (42%)
• Similarity: 264/474 - (55%)
• Gaps: 88/474 - (18%)

  Fly    21 RLSGHGSL-GLSSGSAAYT-----THSGGHTGRSGPATGHSGHSSTHGSAATMHHQSLQSDFQ-- 77
            ||...|.| .:::.:.||:     |:|...|..:.|      :.||:.....:||||...:||
Mouse    27 RLMQLGCLESVANSTVAYSSSSPLTYSTTGTEFASP------YFSTNHQYTPLHHQSFHYEFQHS 85

  Fly    78 -PPYFPPPF-----HHSTQSPPQQQISGYLQNHGALEYLGTDPYGQPLSSLHHAPLHHYNQLAG- 135
             |...|..:     |||.|.        |.|.|          :|:|...::   ||:...|..
Mouse    86 HPAVTPDAYSLNSLHHSQQY--------YQQIH----------HGEPTDFIN---LHNARALKSS 129

  Fly   136 -LRSTQDQLGIHRTHREAELQGHVTQLSHGFPY---TDRRSDYGSAISAGAAHGTRLGHEHESLA 196
             |...:.:||....:|..:|    :.:|||..|   .|:|...|.::...||
Mouse   130 CLDEQRRELGCLDAYRRHDL----SLMSHGSQYGMHPDQRLLPGPSLGLAAA------------- 177

  Fly   197 LHQALQNAVDDVQAPALDDNVAFMSDLPLIKSMKSGKEAGNIGSG-----SPSEVFCAVPGRLSL 256
                   ..||:|.     :|.....:.|      ..:.|.|..|     :|:::||:|||||||
Mouse   178 -------GADDLQG-----SVEAQCGIVL------NGQGGVIRRGGTCVVNPTDLFCSVPGRLSL 224

  Fly   257 LSSTSKYKVTIAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRLLREKLEKIGLNLPAGRRKAAN 321
            ||||||||||||||:||||||||||||||||:|||||||||||.|||||:::|||||||||||||
Mouse   225 LSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAAN 289

  Fly   322 VTLLTSLVEGEATHLAKDFHFVCETEFPARQLAEYIVRHQTEPQDSYRRKELILHSQQITKELMQ 386
            ||||||||||||.|||:||.:.|||||||:.:.|::.|...|.::...||::||.::||.||...
Mouse   290 VTLLTSLVEGEALHLARDFGYTCETEFPAKAVGEHLARQHMEQKEQTARKKMILATKQICKEFQD 354

  Fly   387 ILSQDRTTHFGTRSQHLLEPSMQRHLTHFSLITHGFGSPAIMAVLHAFQTFLNESLNYLEKLYPS 451
            :|||||:....:|...:|:..:|||||||||||||||:|||.|.|..|||.|:|.||||||....
Mouse   355 LLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTVLSEMLNYLEKHTTH 419

  Fly   452 NGGGMVSSSLDKSKIDNEK 470
            ..||...|.  :...::||
Mouse   420 KNGGAADSG--QGHANSEK 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfAP-2	NP_001262178.1	TF_AP-2	247..441	CDD:397406	134/193 (69%)
Tfap2d	NP_001366002.1	TF_AP-2	215..409	CDD:397406	134/193 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850560
Domainoid	1	1.000	277	1.000	Domainoid score	I1710
eggNOG	1	0.900	-	-		E1_KOG3811
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	324	1.000	Inparanoid score	I2473
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D287275at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42961
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10812
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X400
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.860