Protein Alignment TfAP-2 and Tfap2c

DIOPT Version :9

• Sequence 1: NP_001262178.1
• Gene: TfAP-2 / 40398
• FlyBaseID: FBgn0261953
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_001153168.1
• Gene: Tfap2c / 21420
• MGIID: 106032
• Length: 488
• Species: Mus musculus
• Alignment Length: 464
• Identity: 200/464 - (43%)
• Similarity: 262/464 - (56%)
• Gaps: 58/464 - (12%)

  Fly    31 SSGSAAYTTHSGGHTGRSGPATGHSGHSSTH--GSAATMHHQSLQSDFQPPYFPPPFHHSTQSPP 93
            |..|:....|.....|  .|...|......|  ..|..:.|..:.....|||||||:
Mouse    49 SKDSSPQDRHDSSSNG--NPRIPHLSSPGQHLYSPAPPLSHTGVAEYQPPPYFPPPY-------- 103

  Fly    94 QQQISGYLQNHGALEYLGTDPYGQPLSSLHHAPLHHYNQLA--GLRSTQ-DQLGIHRTHREAELQ 155
             ||:: |.|:.....:|| :.|...::.||........|.|  |.:|.: ..|..|.: |.|.|.
Mouse   104 -QQLA-YSQSADHYSHLG-EAYAAAMNPLHQPAATGSQQQAWPGRQSQEGSSLASHHS-RSASLI 164

  Fly   156 GHVTQLSHGFPYTD----RRSD----YGSAISAGAAHGTRLGHEHESLALHQALQNAVDDVQAPA 212
            .|::.|..|.....    ||||    :..|:.||.|         |:|.||: :.:.:::||  .
Mouse   165 PHISGLEGGSVSARREVYRRSDLLLPHAHALEAGLA---------ENLGLHE-MAHPIEEVQ--N 217

  Fly   213 LDDNVAFMSDLPLIKSMKSGKEAGNIGSG----------SPSEVFCAVPGRLSLLSSTSKYKVTI 267
            :||....:.|..:|:..........:|..          :||||||:|||||||||||||||||:
Mouse   218 VDDAHLLLHDQTVIRKGPISMTKNPLGLPCQKDLVGVVMNPSEVFCSVPGRLSLLSSTSKYKVTV 282

  Fly   268 AEVQRRLSPPECLNASLLGGVLRRAKSKNGGRLLREKLEKIGLNLPAGRRKAANVTLLTSLVEGE 332
            ||||||||||||||||||||||||||||||||.|||||:||||||||||||||:|||||||||||
Mouse   283 AEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAAHVTLLTSLVEGE 347

  Fly   333 ATHLAKDFHFVCETEFPARQLAEYIVR-HQTEPQDSYRRKELILHSQQITKELMQILSQDRTTHF 396
            |.|||:||.:|||.|||::.:|:|:.| |.....:...||.::|.:||:.||...:|.||||.:.
Mouse   348 AVHLARDFAYVCEAEFPSKAVADYLTRPHLGGRNEMATRKSMLLAAQQVCKEFTDLLHQDRTPNG 412

  Fly   397 GTRSQHLLEPSMQRHLTHFSLITHGFGSPAIMAVLHAFQTFLNESLNYLEKLYPSNGGGMVSSSL 461
            ..|...:|||::|..|:|||||||||||.||.|.:.|.|.::.|:|..::|.|.:.|
Mouse   413 NNRPAQVLEPNIQNCLSHFSLITHGFGSQAICAAVSAVQNYIKEALIAIDKSYMNPG-------- 469

  Fly   462 DKSKIDNEK 470
            |:|..|:.|
Mouse   470 DQSPADSSK 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfAP-2	NP_001262178.1	TF_AP-2	247..441	CDD:397406	131/194 (68%)
Tfap2c	NP_001153168.1	TF_AP-2	260..458	CDD:281315	134/197 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850558
Domainoid	1	1.000	277	1.000	Domainoid score	I1710
eggNOG	1	0.900	-	-		E1_KOG3811
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	324	1.000	Inparanoid score	I2473
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D287275at33208
OrthoFinder	1	1.000	-	-		FOG0000991
OrthoInspector	1	1.000	-	-		otm42961
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10812
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10438
SonicParanoid	1	1.000	-	-		X400
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.930