Protein Alignment TfAP-2 and Tfap2b

DIOPT Version :9

• Sequence 1: NP_001262178.1
• Gene: TfAP-2 / 40398
• FlyBaseID: FBgn0261953
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: XP_006495554.1
• Gene: Tfap2b / 21419
• MGIID: 104672
• Length: 475
• Species: Mus musculus
• Alignment Length: 442
• Identity: 204/442 - (46%)
• Similarity: 261/442 - (59%)
• Gaps: 57/442 - (12%)

  Fly    40 HSGGHTGRSGPATGHSGHSSTHGSAATMHHQSL-------QSDFQPPYFPPPF----HHSTQSPP 93
            |:.....|......||...|..||.:...:.|.       .|||||||||||:    :|.:|.|
Mouse    31 HTYSSMDRHDGVPSHSSRLSQLGSVSQGPYSSAPPLSHTPSSDFQPPYFPPPYQPLPYHQSQDP- 94

  Fly    94 QQQISGYLQNHGALEYLGTDPYGQPLSSLHHAPLHHYNQLAGLRSTQDQLGIHRTHREAELQGHV 158
                    .:|      ..|||.  |:.||....|.:.|    |..| ::|........:.:..:
Mouse    95 --------YSH------VNDPYS--LNPLHQPQQHPWGQ----RQRQ-EVGSEAGSLLPQPRAAL 138

  Fly   159 TQLSHGFPYTDRRSDYGS-----AISAGAAHGTRLGHEHESLALHQALQNAVDDVQA-------- 210
            .|||.    .|.|.||.|     .:...|.||...| ..:||:||......::|||:
Mouse   139 PQLSG----LDPRRDYHSVRRPDVLLHSAHHGLDAG-MGDSLSLHGLGHPGMEDVQSVEDANNSG 198

  Fly   211 -PALDDNVAFMSDLP--LIKSMKSGKEAGNIG--SGSPSEVFCAVPGRLSLLSSTSKYKVTIAEV 270
             ..||.:|.....:|  .:.|:...|: |.:|  |.:..||||:|||||||||||||||||:.||
Mouse   199 MNLLDQSVIKKVPVPPKSVTSLMMNKD-GFLGGMSVNTGEVFCSVPGRLSLLSSTSKYKVTVGEV 262

  Fly   271 QRRLSPPECLNASLLGGVLRRAKSKNGGRLLREKLEKIGLNLPAGRRKAANVTLLTSLVEGEATH 335
            |||||||||||||||||||||||||||||.|||:|||||||||||||||||||||||||||||.|
Mouse   263 QRRLSPPECLNASLLGGVLRRAKSKNGGRSLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVH 327

  Fly   336 LAKDFHFVCETEFPARQLAEYIVRHQTEPQDSYRRKELILHSQQITKELMQILSQDRTTHFGTRS 400
            ||:||.::|||||||:.::||:.|..|:|.|.:.||.::|.::|:.||...:|:||||....:|.
Mouse   328 LARDFGYICETEFPAKAVSEYLNRQHTDPSDLHSRKNMLLATKQLCKEFTDLLAQDRTPIGNSRP 392

  Fly   401 QHLLEPSMQRHLTHFSLITHGFGSPAIMAVLHAFQTFLNESLNYLEKLYPSN 452
            ..:|||.:|..||||||||||||:|||.|.|.|.|.:|.|:|..::|::.:|
Mouse   393 SPILEPGIQSCLTHFSLITHGFGAPAICAALTALQNYLTEALKGMDKMFLNN 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfAP-2	NP_001262178.1	TF_AP-2	247..441	CDD:397406	136/193 (70%)
Tfap2b	XP_006495554.1	TF_AP-2	239..433	CDD:397406	136/193 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850561
Domainoid	1	1.000	277	1.000	Domainoid score	I1710
eggNOG	1	0.900	-	-		E1_KOG3811
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	324	1.000	Inparanoid score	I2473
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000991
OrthoInspector	1	1.000	-	-		otm42961
orthoMCL	1	0.900	-	-		OOG6_105211
Panther	1	1.100	-	-	O	PTHR10812
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X400
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.790