DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TfAP-2 and aptf-1

DIOPT Version :9

Sequence 1:	NP_001262178.1	Gene:	TfAP-2 / 40398	FlyBaseID:	FBgn0261953	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_495300.2	Gene:	aptf-1 / 187043	WormBaseID:	WBGene00019424	Length:	365	Species:	Caenorhabditis elegans

Alignment Length:	212	Identity:	111/212 - (52%)
Similarity:	160/212 - (75%)	Gaps:	5/212 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 EVFCAVPGRLSLLSSTSKYKVTIAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRLLREKLEKIG 309
            ||:|.||||.||||||:||:||:||:|||:|||||||||||||:||:||||:||:.||:.|:|:|
Worm   152 EVYCTVPGRTSLLSSTTKYRVTVAEIQRRISPPECLNASLLGGILRKAKSKDGGKTLRDSLKKLG 216

  Fly   310 LNLPAGRRKAANVTLLTSLVEGEATHLAKDFHFVCETEFPARQLAEYIVRHQ--TEPQDSYRRKE 372
            |.|||||||.||||..|:|||.||.|:||:|..|||.||.:|::..|:.:..  .:| |..:|:.
Worm   217 LTLPAGRRKQANVTAWTALVEEEAIHMAKEFALVCEKEFHSREIGIYLTKTSLAIDP-DVVKRRT 280

  Fly   373 LILHSQQITKELMQILSQDRT--THFGTRSQHLLEPSMQRHLTHFSLITHGFGSPAIMAVLHAFQ 435
            .:..|:::..||.::||.|||  |.:..|:...::||:|:||:||:|:|||||:.|:.|||.:.:
Worm   281 ALEMSRKVVGELAELLSCDRTPLTPYFPRNMLPIDPSVQQHLSHFTLMTHGFGNVAMSAVLESVK 345

  Fly   436 TFLNESLNYLEKLYPSN 452
            ..::||:.|:::....|
Worm   346 LMIDESIKYIDRCCSQN 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TfAP-2	NP_001262178.1	TF_AP-2	247..441	CDD:397406	105/197 (53%)
aptf-1	NP_495300.2	TF_AP-2	152..355	CDD:281315	109/203 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167680
Domainoid	1	1.000	211	1.000	Domainoid score	I1632
eggNOG	1	0.900	-	-		E1_KOG3811
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D287275at33208
OrthoFinder	1	1.000	-	-		FOG0000991
OrthoInspector	1	1.000	-	-		oto18538
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10812
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10438
SonicParanoid	1	1.000	-	-		X400
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.840