Protein Alignment TfAP-2 and tfap2e

DIOPT Version :9

• Sequence 1: NP_001262178.1
• Gene: TfAP-2 / 40398
• FlyBaseID: FBgn0261953
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_001123400.1
• Gene: tfap2e / 100170172
• XenbaseID: XB-GENE-876803
• Length: 434
• Species: Xenopus tropicalis
• Alignment Length: 471
• Identity: 219/471 - (46%)
• Similarity: 278/471 - (59%)
• Gaps: 80/471 - (16%)

  Fly    25 HGSLGLSSGSAAYTTHSGGHTGR-----SGPATGHSGHSSTHGSAATMHHQSLQSDFQPPYFPPP 84
            |....:....|.....|||...:     .||          :.||..:.| :..|||||||||||
 Frog     4 HAYSAMDRSEALNGAASGGRLSQLSSLNQGP----------YSSAPPLCH-TPASDFQPPYFPPP 57

  Fly    85 FHHSTQSPPQQQISGYLQNHGALEYLGTDPYGQPLSSLH-------HAPLHHYNQLAGLRSTQDQ 142
            :.....|..|.|.|||       .:|| |||.. ::|:|       |.|          ||.|::
 Frog    58 YPQPPLSYSQSQESGY-------PHLG-DPYSS-INSIHQHQQPSWHTP----------RSRQEE 103

  Fly   143 LG-IHRTHREAELQGHVTQLSHGFPYTDRRSDYG--SAISAGAAHGTRLGHE--HESLALHQALQ 202
            .| :.:|||...|              |.|.|||  |.:..|...|   ||.  ..||::|....
 Frog   104 TGLLSQTHRGLSL--------------DPRRDYGGMSRLIPGLTDG---GHSLADSSLSIHALSH 151

  Fly   203 NAVDDVQAPALDDNVAFMSDLPLIK----------SMKS----GKEAGNIGSGSPSEVFCAVPGR 253
            ::::|:|  :||::...:.|..:||          ||.|    .||:...|..:|:||||:||||
 Frog   152 HSLEDMQ--SLDESGVSILDQSVIKKVPIPSKNNGSMMSVLSMHKESLIGGVTNPNEVFCSVPGR 214

  Fly   254 LSLLSSTSKYKVTIAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRLLREKLEKIGLNLPAGRRK 318
            |||||||||||||:.|||||||||||||||||||||||||||||||.|||:||||||||||||||
 Frog   215 LSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRK 279

  Fly   319 AANVTLLTSLVEGEATHLAKDFHFVCETEFPARQLAEYIVRHQTEPQDSYRRKELILHSQQITKE 383
            |||||||||||||||.|||:||.:||||||||:..|||:.|..::|.:.:.||.::|.::||.||
 Frog   280 AANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHSDPTELHARKNMLLATKQICKE 344

  Fly   384 LMQILSQDRTTHFGTRSQHLLEPSMQRHLTHFSLITHGFGSPAIMAVLHAFQTFLNESLNYLEKL 448
            ...:|:|||:....:|...:|||.:|..||||||||||||.|||.|.|.|||.:|.|||..::|:
 Frog   345 FADLLAQDRSPLGNSRPSLILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGMDKI 409

  Fly   449 YPSNGGGMVSSSLDKS 464
            :.|:.|...|::..||
 Frog   410 FMSSTGNGHSAAESKS 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfAP-2	NP_001262178.1	TF_AP-2	247..441	CDD:397406	137/193 (71%)
tfap2e	NP_001123400.1	TF_AP-2	206..404	CDD:281315	141/197 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	277	1.000	Domainoid score	I1688
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	338	1.000	Inparanoid score	I2326
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D287275at33208
OrthoFinder	1	1.000	-	-		FOG0000991
OrthoInspector	1	1.000	-	-		otm48084
Panther	1	1.100	-	-	LDO	PTHR10812
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10438
SonicParanoid	1	1.000	-	-		X400
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.100