DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EMC10 and SMC1

DIOPT Version :9

Sequence 1:	NP_730662.2	Gene:	EMC10 / 40396	FlyBaseID:	FBgn0052441	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_651211.2	Gene:	SMC1 / 42853	FlyBaseID:	FBgn0040283	Length:	1238	Species:	Drosophila melanogaster

Alignment Length:	143	Identity:	31/143 - (21%)
Similarity:	56/143 - (39%)	Gaps:	37/143 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 LALGNEFYRLKATVVYSNGA-----KAQFITSNKACRL------LQAQLNDVLWVSLEPSGYVT- 130
            |||...||:....:  |.|:     ||:........:|      ||.:|.:::..|.:.|...|
  Fly   665 LALDGTFYQKSGLI--SGGSHDLARKAKRWDEKHMAQLKMQKERLQEELKELVKKSRKQSELATV 727

  Fly   131 -----GITVSQDTAPATIECTQEDV----NKLLETQFSTDVLIRHAELAPVPDTAGFIQKVERER 186
                 |:......:...:|.:::.:    |:|.:.|...|      |..|.      |.::||..
  Fly   728 ESQIKGLENRLKYSMVDLESSKKSISQYDNQLQQVQSQLD------EFGPK------ILEIERRM 780

  Fly   187 EARER--GEVRDN 197
            :.||.  .|:::|
  Fly   781 QNREEHIQEIKEN 793

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EMC10	NP_730662.2	None
SMC1	NP_651211.2	Smc	26..1216	CDD:224117	31/143 (22%)
		ABC_SMC1_euk	27..>171	CDD:213242
		SMC_hinge	535..653	CDD:214944
		DUF4700	<697..>810	CDD:292399	22/109 (20%)
		ABC_SMC1_euk	<1130..1232	CDD:213242
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1196
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900