Protein Alignment CRIF and GADD45GIP1

DIOPT Version :10

• Sequence 1: NP_649333.1
• Gene: CRIF / 40395
• FlyBaseID: FBgn0037102
• Length: 232
• Species: Drosophila melanogaster
• Sequence 2: NP_443082.2
• Gene: GADD45GIP1 / 90480
• HGNCID: 29996
• Length: 222
• Species: Homo sapiens
• Alignment Length: 167
• Identity: 54/167 - (32%)
• Similarity: 82/167 - (49%)
• Gaps: 22/167 - (13%)

  Fly    72 WIHLTEKYQRQAFGRYGAQSNVNPKICFDSHGEKDSRQVMQLE--------TLLKMLEKNRAQKA 128
            | .|..:|..:.|.||||.|.|.|...:.|     ..|:.:||        :|..|.|..|.::.
Human    50 W-QLGPRYAAKQFARYGAASGVVPGSLWPS-----PEQLRELEAEEREWYPSLATMQESLRVKQL 108

  Fly   129 EELARINAREEDIAKKMEKLTQ----WKADLHAKIAKREADAAAAIQRKERLVEEVRRHFGFKVD 189
            .|..:...||:.||:.|.|:.|    |:........|.:||.    :|:.||..|.:...|::||
Human   109 AEEQKRREREQHIAECMAKMPQMIVNWQQQQRENWEKAQADK----ERRARLQAEAQELLGYQVD 169

  Fly   190 TRDERFKEMLEQKEKEDKKKQKEAKRKAKEEKMMAKL 226
            .|..||:|:|:..||:::|:.||.|:|.|:|...|.|
Human   170 PRSARFQELLQDLEKKERKRLKEEKQKRKKEARAAAL 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRIF	NP_649333.1	CR6_interact	47..231	CDD:431088	54/167 (32%)
GADD45GIP1	NP_443082.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..46
		CR6_interact	48..190	CDD:431088	46/149 (31%)
		Nuclear localization signal. /evidence=ECO:0000255	184..200		7/15 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..222		9/19 (47%)