DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CRIF and gadd45gip1

DIOPT Version :9

Sequence 1:	NP_649333.1	Gene:	CRIF / 40395	FlyBaseID:	FBgn0037102	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	XP_001345133.4	Gene:	gadd45gip1 / 402803	ZFINID:	ZDB-GENE-091204-282	Length:	240	Species:	Danio rerio

Alignment Length:	235	Identity:	73/235 - (31%)
Similarity:	114/235 - (48%)	Gaps:	45/235 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SVVTRLPALRSCAQYS-SAAKAELPASLVGDVDVEPTYPQTVDRSGLQPQHKNVLLNKLPY---- 66
            ::...|.:.|:.:.:| :...:.|||:::...:..|           :|...|:   |.||
Zfish    19 NMAASLLSRRTASSFSFTKLNSLLPAAVIQIANYNP-----------RPLRLNL---KDPYIPDK 69

  Fly    67 --QEPHSWIHLTEKYQRQAFGRYGAQSNVNPKICFDSHGEKDSRQVMQLETLL-----------K 118
              :....| ..|||::|:.|||||..|.|||...:.|        ..:||.|:           :
Zfish    70 ESERTPEW-QKTEKFERRLFGRYGRASGVNPVKLWPS--------AARLEELMAEEREWHPPVEQ 125

  Fly   119 MLEKNRAQKAEELARINAREEDIAKKMEKLTQWKADLHAKIAKREADAAA--AIQRKERLVEEVR 181
            ||:....::.|:..|...||:.||:.|.|:.:..||.  |..||||...|  ..|::.||:...|
Zfish   126 MLQNIAERQMEKEKRRIEREKTIAESMAKMPKLIADW--KKQKREAKQKANEEKQKQVRLLAMAR 188

  Fly   182 RHFGFKVDTRDERFKEMLEQKEKEDKKKQKEAKRKAKEEK 221
            ..|||.||.|..:||||:.:.|||:||::|..||:.|||:
Zfish   189 ERFGFAVDPRSVKFKEMVAEIEKEEKKQRKLLKRQKKEEE 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CRIF	NP_649333.1	CR6_interact	29..231	CDD:287157	70/212 (33%)
gadd45gip1	XP_001345133.4	CR6_interact	20..238	CDD:287157	73/234 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592416
Domainoid	1	1.000	86	1.000	Domainoid score	I8087
eggNOG	1	0.900	-	-		E1_KOG4848
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I5142
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1431395at2759
OrthoFinder	1	1.000	-	-		FOG0007222
OrthoInspector	1	1.000	-	-		oto40232
orthoMCL	1	0.900	-	-		OOG6_109424
Panther	1	1.100	-	-	LDO	PTHR31761
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5556
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.830