Protein Alignment CapaR and Gpr39

DIOPT Version :10

• Sequence 1: NP_996140.1
• Gene: CapaR / 40393
• FlyBaseID: FBgn0037100
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_081953.2
• Gene: Gpr39 / 71111
• MGIID: 1918361
• Length: 456
• Species: Mus musculus
• Alignment Length: 405
• Identity: 98/405 - (24%)
• Similarity: 186/405 - (45%)
• Gaps: 34/405 - (8%)

  Fly    69 VLITIIFGGIFITGVVGN---LLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFGLPTEVF-LY 129
            :.:.:::..||:.|::||   :.|..|:.:...:......::.|||.||:|..|.|:|.|.: :.
Mouse    31 ITLILVYLIIFVVGILGNSVTIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSII 95

  Fly   130 WHQYPDLFGMPFCKIRAFISEACTYVSVFTIVAFSMERFLAICHPLHLYAMVGFKRAIRIITALW 194
            |:..........||:..|:.|.|:|.::..::..|.||::|||||....|:.|.::...:|..:|
Mouse    96 WNPLTTPSYALSCKLHTFLFETCSYATLLHVLTLSFERYIAICHPFKYKAVSGPRQVKLLIGFVW 160

  Fly   195 IVSFISAIPFGLLSDIQY----------LNYPLDHSRIEE---SAFCSMSPKIVNEIPVFEVS-- 244
            :.|.:.|:|......|:|          ||..|..:|..:   ::..|:...:.|...||:.|
Mouse   161 VTSALVALPLLFAMGIEYPLVNVPTHKGLNCNLSRTRHHDEPGNSNMSICTNLSNRWEVFQSSIF 225

  Fly   245 --FCIFFVIPMILIILLYGRMGAKIRSR--TNQKLGVQQGTNNRETRNSQMRKKTVIRMLAAVVI 305
              |.::.|:...:..:.:..|...::|:  |....|.|......|:..|:..::..|..|..:|:
Mouse   226 GAFAVYLVVLASVAFMCWNMMKVLMKSKQGTLAGTGPQLQLRKSESEESRTARRQTIIFLRLIVV 290

  Fly   306 TFFVCWFPFHLQRLIFLYAKNMD---NYLDINEALFSIAGFAYYVSCTVNPIVYSVMSRRYRVAF 367
            |..|||.|..::|::.......|   .|......|...:...:|:|..|||::|:|.|:::|..|
Mouse   291 TLAVCWMPNQIRRIMAAAKPKHDWTRTYFRAYMILLPFSDTFFYLSSVVNPLLYNVSSQQFRKVF 355

  Fly   368 RELLCGKAVGAYYNSGFARDHSSF---RESSAYDRVHSVHVRASQHPNKFETDSSSANRVLIKKT 429
            .::||.:....:.|.. .|..:.|   ::|::..|...:.: ||:..|   :.|...|:|.:...
Mouse   356 WQVLCCRLTLQHANQE-KRQRARFISTKDSTSSARSPLIFL-ASRRSN---SSSRRTNKVFLSTF 415

  Fly   430 YSLPLPKNADSTVLS 444
            .:...|..|....||
Mouse   416 QTEAKPGEAKPQPLS 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tmA_capaR	83..367	CDD:320262	77/309 (25%)
		TM helix 2	103..129	CDD:320262	10/26 (38%)
		TM helix 3	142..172	CDD:320262	10/29 (34%)
		TM helix 4	184..206	CDD:320262	5/21 (24%)
		TM helix 5	237..266	CDD:320262	6/32 (19%)
		TM helix 6	291..321	CDD:320262	9/29 (31%)
		TM helix 7	335..360	CDD:320262	8/24 (33%)
Gpr39	NP_081953.2	7tmA_GPR39	31..355	CDD:320263	80/323 (25%)
		TM helix 1	31..58	CDD:320263	6/26 (23%)
		TM helix 2	68..94	CDD:320263	10/25 (40%)
		TM helix 3	108..138	CDD:320263	10/29 (34%)
		TM helix 4	150..172	CDD:320263	5/21 (24%)
		TM helix 5	217..246	CDD:320263	5/28 (18%)
		TM helix 6	276..306	CDD:320263	9/29 (31%)
		TM helix 7	323..348	CDD:320263	8/24 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	415..456		4/16 (25%)