DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and Olfr701

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_001347676.1	Gene:	Olfr701 / 66786	MGIID:	3030535	Length:	316	Species:	Mus musculus

Alignment Length:	349	Identity:	72/349 - (20%)
Similarity:	133/349 - (38%)	Gaps:	102/349 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 VLITIIFGG------------IFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFG 121
            :|:.|:.|.            :::..::.|.|:.:||...:.:|......|..|::.|||:....
Mouse    13 ILVGILDGSGSPELLCATVTTLYMLALISNGLLLLVITVDARLHVPMYLLLRQLSLIDLLFTSVV 77

  Fly   122 LPTEV--FLYWHQYPDLFGMPFCKIRAFISEACTYVSVFTIVAFSMERFLAICHPLHLYAMVGFK 184
            .|..|  ||.........|   |.::.|.:..........:...:.:|::||||||: |.:....
Mouse    78 TPNTVVDFLLRDNTISFEG---CALQLFSAMTLGGAEDLLLAFMAYDRYVAICHPLN-YMIFMSP 138

  Fly   185 RAIRIITAL-WIVSFISAI---------PFGLLSDIQYLNYPLDHSRIEESAFCSMSPKI----- 234
            :|.|::.|: ||::.:||:         ||.:..:|::|             .|.:.|.:
Mouse   139 KACRLMVAISWILASLSALGHTVYTMHFPFCMSQEIRHL-------------LCEVPPLLKLACA 190

  Fly   235 ---VNEIPVFEVSFCIFFVIPMILIILLY--------------GRMGAKIRSRTNQKLGVQQGTN 282
               ..|:.|: |:..||.::|:..||..|              ||..|.:
Mouse   191 DTSQYELMVY-VTGVIFLLLPLSAIITSYSLILFTVLHMPSNEGRKKALV--------------- 239

  Fly   283 NRETRNSQMRKKTVIRMLAAVVITFFVCWFPFHLQRLIFLYAKNMDNYLDINEALFSIAGFAYYV 347
               |.:|.:   ||:.|........:|....||        :...||.:.:         |...|
Mouse   240 ---TCSSHL---TVVGMFYGGATFMYVLPSSFH--------SPKQDNIISV---------FYTIV 281

  Fly   348 SCTVNPIVYSVMSRRYRVAFRELL 371
            :..:||::||:.::....|.|.:|
Mouse   282 TPALNPLIYSLRNKEVIGAVRRVL 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	69/321 (21%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	64/304 (21%)
Olfr701	NP_001347676.1	7tmA_OR2T-like	26..300	CDD:320543	66/329 (20%)
		TM helix 1	26..52	CDD:320543	4/25 (16%)
		TM helix 2	59..85	CDD:320543	7/25 (28%)
		TM helix 3	97..127	CDD:320543	4/29 (14%)
		TM helix 4	140..161	CDD:320543	7/20 (35%)
		TM helix 5	195..225	CDD:320543	9/30 (30%)
		TM helix 6	232..262	CDD:320543	9/50 (18%)
		TM helix 7	269..294	CDD:320543	8/33 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000