DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and Nmur1

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	XP_017452122.1	Gene:	Nmur1 / 65276	RGDID:	619867	Length:	414	Species:	Rattus norvegicus

Alignment Length:	433	Identity:	128/433 - (29%)
Similarity:	211/433 - (48%)	Gaps:	61/433 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 GTFNCSPKEFVAF----------------VLGPQTLPLYKAVLITIIFGGIFITGVVGNLLVCIV 92
            |..:|:..||...                .||||.:..:..:.:|.:.  ||:.|.:||.|.|.|
  Rat    11 GLLSCNDSEFKEHFDLEDLNLTHEDLRLKYLGPQQVKQFLPICVTYLL--IFVVGTLGNGLTCTV 73

  Fly    93 IIRHSAMHTATNYYLFSLAVSDLLYLLFGLPTEVFLYWHQYPDLFGMPFCKIRAFISEACTYVSV 157
            |:|..||||.||:|||||||||||.||.|||.|::...|.||...|...|..|..:.|.....||
  Rat    74 ILRQKAMHTPTNFYLFSLAVSDLLVLLVGLPLELYEMQHNYPFQLGAGGCYFRILLLETVCLASV 138

  Fly   158 FTIVAFSMERFLAICHPLHLYAMVGFKRAIRIITALWIVSFISAIPFGLLSDIQYLNYPLDHSRI 222
            ..:.|.|:||::|:.|||...:::......|::.|:|:.:.:.::|...|..:..|..|. ...:
  Rat   139 LNVTALSVERYVAVVHPLQAKSVMTRTHVRRMLGAIWVFAILFSLPNTSLHGLSPLYVPC-RGPV 202

  Fly   223 EESAFCSM-SPKIVNEIPVFEVSFCIFFVIPMILIILLYGRMGAKIRSRTNQKLGVQQGTNNR-- 284
            .:|..|:: .|:...:: |.:.:..:||.:||:.|.:||..:|.::|   .:::.:|:....|
  Rat   203 PDSVTCTLVRPQFFYKL-VIQTTILLFFCLPMVTISVLYLLIGLRLR---RERILLQEEVKGRIS 263

  Fly   285 ------ETRNSQMR---KKTVIRMLAAVVITFFVCWFPFHLQRLIFLYAKNMDNYLDIN-EALFS 339
                  ..|:.|:|   ::.|.:||.|:||.|..||.|||..||::....:..:.|.:. :::..
  Rat   264 AAARQASHRSIQLRDRERRQVTKMLIALVIVFGTCWVPFHADRLMWSMVSHWTDGLRLAFQSVHL 328

  Fly   340 IAGFAYYVSCTVNPIVYSVMSRRYRVAFRELLCGKAVGAYYNSGFARDHSSFRESSAYDRVHSVH 404
            .:|...|:....||::|::||.|:|.:|||.|   .:|.         ....|....:|. || |
  Rat   329 ASGVFLYLGSAANPVLYNLMSTRFRESFRETL---GLGT---------RCCHRHQPRHDS-HS-H 379

  Fly   405 VRASQHPNKFETDSSSANRVLIKKTYSLPLPKNADSTVLSTTD 447
            :|.:       |.|:..:|    .:..:||.:|.|......||
  Rat   380 LRLT-------TVSTLCDR----NSRDVPLAENRDPGCEQETD 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	100/301 (33%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	91/283 (32%)
Nmur1	XP_017452122.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338871
Domainoid	1	1.000	183	1.000	Domainoid score	I3347
eggNOG	1	0.900	-	-		E33208_3BGH7
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3505
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	1	1.000	-	-		FOG0001494
OrthoInspector	1	1.000	-	-		mtm8974
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24243
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X673
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.860