DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and Nmur2

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_071611.3	Gene:	Nmur2 / 64042	RGDID:	621155	Length:	395	Species:	Rattus norvegicus

Alignment Length:	330	Identity:	119/330 - (36%)
Similarity:	202/330 - (61%)	Gaps:	22/330 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 SPKEFVAFVLGPQTLPLYKAVLITIIFGGIFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVS 113
            |.:|::|.:.||:...|  ::.:::.:..||:.||:||||||:||:||..:.|.|||||||||||
  Rat    20 STEEYLAHLCGPKRSDL--SLPVSVAYALIFLVGVMGNLLVCMVIVRHQTLKTPTNYYLFSLAVS 82

  Fly   114 DLLYLLFGLPTEVFLYWHQYPDLFGMPFCKIRAFISEACTYVSVFTIVAFSMERFLAICHPLHLY 178
            |||.||.|:|.|::..||.||.|||...|..:..:.|...:.|:.::...|:||::||.||....
  Rat    83 DLLVLLLGMPLEIYEMWHNYPFLFGPVGCYFKTALFETVCFASILSVTTVSVERYVAIVHPFRAK 147

  Fly   179 AMVGFKRAIRIITALWIVSFISAIPFGLLSDIQYLNYPLDHSRIEESAFCSMS-PKIVNEIPVFE 242
            .....:||:||::.:|..|.:.::|...:..|::.::| :.|.:..||.|::: |..|..:.:..
  Rat   148 LESTRRRALRILSLVWSFSVVFSLPNTSIHGIKFQHFP-NGSSVPGSATCTVTKPMWVYNLIIQA 211

  Fly   243 VSFCIFFVIPMILIILLYGRMGAKIRSRTNQKLGVQQGTNN--RETRNSQMRKKTVIRMLAAVVI 305
            .|| :|:::||.||.:||..||  :|.:.::.|...:...|  |.:|      |:|.:||..:|:
  Rat   212 TSF-LFYILPMTLISVLYYLMG--LRLKRDESLEANKVAVNIHRPSR------KSVTKMLFVLVL 267

  Fly   306 TFFVCWFPFHLQRLIFLYAKNMDNYLDINEALFS----IAGFAYYVSCTVNPIVYSVMSRRYRVA 366
            .|.:||.|||:.||.|.:   ::.:.:...|:|:    ::|..:|:|..||||:|:::|||:|.|
  Rat   268 VFAICWTPFHVDRLFFSF---VEEWTESLAAVFNLIHVVSGVFFYLSSAVNPIIYNLLSRRFRAA 329

  Fly   367 FRELL 371
            ||.::
  Rat   330 FRNVV 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	109/294 (37%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	101/277 (36%)
Nmur2	NP_071611.3	7tm_4	48..333	CDD:304433	112/297 (38%)
		7tm_1	54..319	CDD:278431	101/277 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	374..395
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338872
Domainoid	1	1.000	183	1.000	Domainoid score	I3347
eggNOG	1	0.900	-	-		E33208_3BGH7
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H49618
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3505
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	1	1.000	-	-		FOG0001494
OrthoInspector	1	1.000	-	-		mtm8974
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24243
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X673
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.860