Protein Alignment CapaR and nmur1b

DIOPT Version :10

• Sequence 1: NP_996140.1
• Gene: CapaR / 40393
• FlyBaseID: FBgn0037100
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: XP_698473.4
• Gene: nmur1b / 569960
• ZFINID: ZDB-GENE-131121-154
• Length: 404
• Species: Danio rerio
• Alignment Length: 387
• Identity: 133/387 - (34%)
• Similarity: 203/387 - (52%)
• Gaps: 60/387 - (15%)

  Fly    18 NTPDTLFATSVSSDPSHGFGEEDYACGTFNCSPKE-------------------FVAFVLGPQTL 63
            ::|.:||...|:               |..||.||                   ::...|||...
Zfish     7 SSPSSLFTVVVN---------------TSWCSTKEEECQNRTANLSDLCLSRSAYLEKYLGPCRS 56

  Fly    64 PLYKAVLITIIFGGIFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFGLPTEVFL 128
            |.:..:.:|.:.  ||:.|||||:|.||||.||..|.|.|||||||||:||||.||.|||.|::.
Zfish    57 PFFLPICVTYLL--IFVVGVVGNILTCIVITRHRIMRTTTNYYLFSLAISDLLVLLLGLPLELYE 119

  Fly   129 YWHQYPDLFGMPFCKIRAFISEACTYVSVFTIVAFSMERFLAICHPLHLYAMVGFKRAIRIITAL 193
            .|..||.|||:..|..:..:.|...:.||..:.|.|.||:.||.||||...:.....|.|:|..|
Zfish   120 LWSNYPFLFGISGCYFKTCLFETVCFASVLNVTALSAERYRAIIHPLHTKHVATSAHAKRVILVL 184

  Fly   194 WIVSFISAIPFGLLSDIQYLNYPLDHSRIEESAFCSMSPKIVNEIPVF----EVSFCIFFVIPMI 254
            |.||.:.|:|...:..::.|. |.......||..|:    :|::..::    :|:..:||::||:
Zfish   185 WAVSLLCALPNTSIHGVEMLK-PRFGLTFPESGVCT----VVHDRWIYNLLVQVTALLFFILPML 244

  Fly   255 LIILLYGRMGAKI---RSRTNQKLGVQQGTNNRETRNSQMRKKTVIRMLAAVVITFFVCWFPFHL 316
            .|.:||..:|.::   |...:.|:.:.|...|:..|:.|     |.:||.|:||.|.:||.|||:
Zfish   245 TISVLYVLIGLQLHRERECFDSKIVLNQDGVNQRARHRQ-----VTKMLCALVIVFGICWAPFHI 304

  Fly   317 QRLIFLYAKNMDNYLDINEALFS----IAGFAYYVSCTVNPIVYSVMSRRYRVAFRELLCGK 374
            .|:::.|   :|::...|..:|.    ::|..:|:|..||||:|::||.|:|..|||::|.|
Zfish   305 DRVMWSY---IDDWTAENHHIFEYVHLLSGVFFYLSSVVNPILYNLMSSRFREMFREVVCQK 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tmA_capaR	83..367	CDD:320262	111/294 (38%)
		TM helix 2	103..129	CDD:320262	19/25 (76%)
		TM helix 3	142..172	CDD:320262	9/29 (31%)
		TM helix 4	184..206	CDD:320262	9/21 (43%)
		TM helix 5	237..266	CDD:320262	9/32 (28%)
		TM helix 6	291..321	CDD:320262	13/29 (45%)
		TM helix 7	335..360	CDD:320262	9/28 (32%)
nmur1b	XP_698473.4	7tm_GPCRs	60..356	CDD:475119	115/310 (37%)
		TM helix 1	62..86	CDD:410628	13/25 (52%)
		TM helix 2	95..117	CDD:410628	17/21 (81%)
		TM helix 3	134..156	CDD:410628	4/21 (19%)
		TM helix 4	179..195	CDD:410628	7/15 (47%)
		TM helix 5	228..251	CDD:410628	7/22 (32%)
		TM helix 6	285..307	CDD:410628	11/21 (52%)
		TM helix 7	324..349	CDD:410628	8/24 (33%)