Protein Alignment CapaR and Ntsr1

DIOPT Version :10

• Sequence 1: NP_996140.1
• Gene: CapaR / 40393
• FlyBaseID: FBgn0037100
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_001102437.1
• Gene: Ntsr1 / 366274
• RGDID: 1306076
• Length: 424
• Species: Rattus norvegicus
• Alignment Length: 439
• Identity: 122/439 - (27%)
• Similarity: 205/439 - (46%)
• Gaps: 69/439 - (15%)

  Fly     1 MNSST-DPTFSELNAS-FTNTPDTLFATSVSSDPSHGFG---EEDYACGTFNCSPKEFVAFVLGP 60
            :|||. ..|..|.:|. |:.....:.||.::...|:|.|   |.|.|                ||
  Rat     3 LNSSVPQGTPGEPDAQPFSGPQSEMEATFLALSLSNGSGNTSESDTA----------------GP 51

  Fly    61 QT-----LPLYKAVLITIIFGGIFITGVVGNLLVCIVIIRH---SAMHTATNYYLFSLAVSDLLY 117
            .:     ..:|..||:|.|:..:|:.|.|||.:....:.|.   .::.:..:|:|.|||:||||.
  Rat    52 NSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLI 116

  Fly   118 LLFGLPTEVFLY-WHQYPDLFGMPFCKIRAFISEACTYVSVFTIVAFSMERFLAICHPLHLYAMV 181
            ||..:|.|::.: |..:|..||...|:...|:.:||||.:...:.:.|:||:||||||.....::
  Rat   117 LLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLM 181

  Fly   182 GFKRAIRIITALWIVSFISAIPFGLLSDIQYLNYPLDH------SRIEESAFCSMSPKIVNEIPV 240
            ...|..:.|:|:|:.|.:.|||......:|..:....|      :.|.::|    :.|:|.::..
  Rat   182 SRSRTKKFISAIWLASALLAIPMLFTMGLQNRSGDGTHPGGLVCTPIVDTA----TVKVVIQVNT 242

  Fly   241 FEVSFCIFFVIPMILIILLYGRMGAKIRSRTNQKLGVQQ------GTNN---RETRNSQMRKKTV 296
            |     :.|:.||::|.:|...:..|:....:|  ..:|      ||:|   ..|.|..:....|
  Rat   243 F-----MSFLFPMLVISILNTVIANKLTVMVHQ--AAEQGRVCTVGTHNGLEHSTFNMTIEPGRV 300

  Fly   297 ------IRMLAAVVITFFVCWFPFHLQRLIFLYA--KNMDNYL-DINEALFSIAGFAYYVSCTVN 352
                  :.:|.||||.|.|||.|:|::||:|.|.  :....:| |.....:.:....:|||..:|
  Rat   301 QALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALFYVSSAIN 365

  Fly   353 PIVYSVMSRRYRVAFRELLCGKAVGAYY----NSGFARDHSSFRESSAY 397
            ||:|:::|..:|..|...|.....|..:    ...|:|..:|...:.|:
  Rat   366 PILYNLVSANFRQVFLSTLACLCPGWRHRRKKRPTFSRKPNSMSSNHAF 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tmA_capaR	83..367	CDD:320262	91/311 (29%)
		TM helix 2	103..129	CDD:320262	13/25 (52%)
		TM helix 3	142..172	CDD:320262	11/29 (38%)
		TM helix 4	184..206	CDD:320262	8/21 (38%)
		TM helix 5	237..266	CDD:320262	6/28 (21%)
		TM helix 6	291..321	CDD:320262	14/35 (40%)
		TM helix 7	335..360	CDD:320262	7/24 (29%)
Ntsr1	NP_001102437.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		7/19 (37%)
		7tmA_NTSR1	65..380	CDD:320477	97/325 (30%)
		TM helix 1	65..92	CDD:320477	9/26 (35%)
		TM helix 2	102..128	CDD:320477	13/25 (52%)
		TM helix 3	142..172	CDD:320477	11/29 (38%)
		TM helix 4	184..206	CDD:320477	8/21 (38%)
		TM helix 5	234..263	CDD:320477	8/33 (24%)
		TM helix 6	301..331	CDD:320477	13/29 (45%)
		Neurotensin binding	326..349		6/22 (27%)
		TM helix 7	348..373	CDD:320477	7/24 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..424		4/18 (22%)