DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-56

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_001023889.1	Gene:	srw-56 / 3565971	WormBaseID:	WBGene00005803	Length:	355	Species:	Caenorhabditis elegans

Alignment Length:	342	Identity:	71/342 - (20%)
Similarity:	141/342 - (41%)	Gaps:	77/342 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 KAVLITIIFGGIFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLF----GLPTEVF 127
            |.::..|   |:||     |:...||:.|.|......|.::..:|:.|.|.||.    .||....
Worm    40 KLIIAAI---GVFI-----NIFHFIVLTRKSMRVYTINLFMIGIAICDFLRLLSVVLGALPHYYK 96

  Fly   128 LYWHQY-------PDLFGMPFCKIRAF---ISEACTYVSVFTIVAFSMERFLAICHPLHLYA--M 180
            ||....       |:.:.:.|..|..:   :|.....::|...||.::.|.:.:.:||...|  :
Worm    97 LYRRSITPHNCIPPETYVVFFVYIYIYSETVSMIAQKLAVSFGVAMAILRVVILKYPLSRRAQDL 161

  Fly   181 VGFKRAIRIITALWIVSFISAIPFGLLSDIQYL---------------NYPLDHSRIEESAFCSM 230
            :.....||||    .:..:..:||... |:|:.               |:. |||...:.:|  .
Worm   162 IMSGSGIRII----FIVCLPHLPFWFF-DLQWTEIRENGTWKPPSGCKNFS-DHSLHTKYSF--E 218

  Fly   231 SPKIVNEIPVFEVSFCIFFVIPMILIILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKT 295
            ..:.:||...| :...:|.|:|.|::.:..|.:...:::.|      :..|::|...::
Worm   219 HGEDINETLRF-MEGILFTVVPSIILPIATGFLIYALKTMT------RAATSSRSNGST------ 270

  Fly   296 VIRMLAAVVITFFVCWFPFHLQRLIFLYAKNMDNYLDINEA----LFSIAGFAYYVSC---TVNP 353
              :|:..:.:||.:..||..:...:        |:|.:::.    |:.|..|..:||.   |::.
Worm   271 --KMVVLITVTFLIATFPLGMTYFV--------NFLGLDDILAFFLYIIGIFCEFVSIINGTLHF 325

  Fly   354 IVYSVMSRRYRVAFREL 370
            ::.:.:|..|:...:|:
Worm   326 VLCACVSSLYQNTVKEM 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	66/324 (20%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	63/308 (20%)
srw-56	NP_001023889.1	7TM_GPCR_Srw	38..346	CDD:370978	71/342 (21%)
		TM helix 2	68..93	CDD:341315	7/24 (29%)
		TM helix 3	121..151	CDD:341315	5/29 (17%)
		TM helix 4	165..181	CDD:341315	4/19 (21%)
		TM helix 5	213..249	CDD:341315	8/38 (21%)
		TM helix 6	264..294	CDD:341315	6/45 (13%)
		TM helix 7	307..332	CDD:341315	5/24 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910