DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-101

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_001024317.1	Gene:	srw-101 / 3565911	WormBaseID:	WBGene00005848	Length:	359	Species:	Caenorhabditis elegans

Alignment Length:	374	Identity:	71/374 - (18%)
Similarity:	133/374 - (35%)	Gaps:	114/374 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 FVAFVLGPQTLPLYKAVLITIIFGGIFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLLY 117
            ||.|:|.              :| .|||     |:...|::.|.|...|:.|.::..:|:.||..
Worm    27 FVNFILS--------------VF-SIFI-----NIFHVIILTRKSMRATSINVFMIGIAICDLCT 71

  Fly   118 LLFGLPTEVFLYW----HQYPDLFGMP-----------------FCKIRAFISEACTYVSVFTIV 161
            .|    |.|:.|:    .:||:.....                 |.:..:::......|.:..:.
Worm    72 TL----TTVYRYFSLVDFEYPECITSDSLVKAYADAMSWSVQYHFKRCSSWLGILMAGVRILIMR 132

  Fly   162 AFSMERFLAICHPLHLYAMVGFKRAIR-IITALWIVSFISAIPFGLLSDIQYLNYPL-----DHS 220
            ..|..:|..|..|:...:::.....|. |:|.:|...         ...|:...|||     :|.
Worm   133 KISNAKFSKIMKPIFGISLMAIVFGISGILTTVWQYE---------CQVIENRTYPLSPNCAEHQ 188

  Fly   221 RIE---------------------ESAFCSMSPKIVNEIPVFEVSFCIFFVIPMILIILLYG-RM 263
            .|.                     .|.|  :|..|::.: :..:||      |::.::|:.. |.
Worm   189 DIHGVFRFSLILRPVSTVADVVILRSYF--ISDSIISSL-IPGISF------PLLAVVLIREIRK 244

  Fly   264 GAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIRMLAAVVITFFVCWFPFHLQRLIFLYAKNMD 328
            ..|.|:|..:.|         .|..::.:.....:::..:.:..|:...|..|..:.    |...
Worm   245 LEKSRTRAIRTL---------STAENEEKYGLSTKLIGLMTVAAFLSETPLGLISIF----KQFF 296

  Fly   329 NYLDINEAL-------FSIAGFAYYVSCTVNPIVYSVMSRRYRVAFREL 370
            ...|||..|       |:|  .|.:|| .::|::..:||.:|....|::
Worm   297 TKGDINIRLLTDLVIYFTI--LATFVS-ILHPVLCLLMSSKYCETLRKM 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	63/342 (18%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	59/326 (18%)
srw-101	NP_001024317.1	7TM_GPCR_Srw	27..345	CDD:370978	71/374 (19%)
		TM helix 2	57..82	CDD:341315	8/28 (29%)
		TM helix 3	102..132	CDD:341315	2/29 (7%)
		TM helix 4	146..166	CDD:341315	3/19 (16%)
		TM helix 5	212..237	CDD:341315	7/33 (21%)
		TM helix 6	263..293	CDD:341315	3/33 (9%)
		TM helix 7	307..332	CDD:341315	6/27 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910