DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and or63b2

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_571205.2	Gene:	or63b2 / 30357	ZFINID:	ZDB-GENE-990415-192	Length:	307	Species:	Danio rerio

Alignment Length:	328	Identity:	63/328 - (19%)
Similarity:	118/328 - (35%)	Gaps:	74/328 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 VLITIIFGGIFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLL--YLLFGLPTEVFLYWH 131
            |::.::|..|    :|.||.:..:|.:..::|.....:|.||..:.|.  :.||
Zfish    27 VVLILLFAAI----IVANLFIIGIIYKEKSLHEPMYVFLCSLCANQLCGSFALF----------- 76

  Fly   132 QYPDLFG-----------MPFCKIRAFISEACTYVSVFTIVAFSMERFLAICHPLHLYAMVGFKR 185
              |.:.|           :..|..:.|...:...|....:...|.:|::||||||..:.::...|
Zfish    77 --PFVLGNMLRSKTPEVPLTVCHAQIFALYSYAQVEFCNLAMMSYDRYVAICHPLEYHRIMSPAR 139

  Fly   186 AIRIITALWIVS-FISAIPFGLLSDIQYLNYPLDHSRIEESAFCS--MSPKIV-------NEIPV 240
            .:.:|...|.:. .|.:..|.:...:::....||      ..:|.  |..|:.       |.|.:
Zfish   140 TMTLIALGWSLEIMILSFSFSVNVQLKFCGNVLD------KVWCDQYMLVKLACSDTTPNNIIGI 198

  Fly   241 FEVSFCIFFVIPMILIILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIRMLAAVVI 305
            ..:...|  ..|:::|...|.::.......|.||                .:|......|..:.:
Zfish   199 TGIPLAI--GPPLLIIFFSYAKILRVCLKFTRQK----------------AKKSLYTCSLHLITL 245

  Fly   306 TFFVCWFPFHLQRLIFLYAKNMDNYLDINEALFSIAGFAYYVSC--TVNPIVYSVMSRRYRVAFR 368
            ..|.....|.|.:..|       ..|.| .|:..:....|::.|  .:|||:|.|.....:.|.:
Zfish   246 LNFTVGCSFELIQSRF-------GKLPI-PAVVRVILSLYFLVCPPLINPIMYGVSLTNIKKALK 302

  Fly   369 ELL 371
            :.:
Zfish   303 KCI 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	59/312 (19%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	56/295 (19%)
or63b2	NP_571205.2	7tm_GPCRs	26..301	CDD:333717	62/322 (19%)
		TM helix 1	26..49	CDD:320351	7/25 (28%)
		TM helix 2	58..80	CDD:320351	7/34 (21%)
		TM helix 3	97..119	CDD:320351	2/21 (10%)
		TM helix 4	142..158	CDD:320351	3/15 (20%)
		TM helix 5	194..217	CDD:320351	5/24 (21%)
		TM helix 6	233..257	CDD:320351	4/23 (17%)
		TM helix 7	269..294	CDD:320351	7/24 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910