Protein Alignment CapaR and Gpr39

DIOPT Version :10

• Sequence 1: NP_996140.1
• Gene: CapaR / 40393
• FlyBaseID: FBgn0037100
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_001107864.1
• Gene: Gpr39 / 288995
• RGDID: 1306745
• Length: 456
• Species: Rattus norvegicus
• Alignment Length: 436
• Identity: 103/436 - (23%)
• Similarity: 189/436 - (43%)
• Gaps: 65/436 - (14%)

  Fly    69 VLITIIFGGIFITGVVGN---LLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFGLPTEVF-LY 129
            :.:|:::..:|:.|::||   :.|..|:.:...:......::.|||.||:|..|.|:|.|.: :.
  Rat    31 ITLTLVYLIVFVVGILGNSVTIRVTQVLQKKGYLQKEVTDHMISLACSDILVFLIGMPMEFYSII 95

  Fly   130 WHQYPDLFGMPFCKIRAFISEACTYVSVFTIVAFSMERFLAICHPLHLYAMVGFKRAIRIITALW 194
            |:..........||:..|:.|.|:|.::..::..|.||::|||||.....:.|..:...:|..:|
  Rat    96 WNPLTTPSYALSCKLHTFLFETCSYATLLHVLTLSFERYIAICHPFRYKDVSGPCQVKLLIGFVW 160

  Fly   195 IVSFISAIPFGLLSDIQYLNYPLDHSRIEESAFCSMSPKIVNEIP----------------VFEV 243
            :.|.:.|:|......|:   |||.:....:...|::|....::.|                ||:.
  Rat   161 VTSALVALPLLFAMGIE---YPLANVPTHKGLNCNLSRTRHHDHPGDSNMSICTNLSSRWEVFQS 222

  Fly   244 S----FCIFFVIPMILIILLYGRMGAKIRSR--TNQKLGVQQGTNNRETRNSQMRKKTVIRMLAA 302
            |    |.::.|:.:.:..:.:..|...::|:  |....|.|......|:..|:..::..|..|..
  Rat   223 SIFGAFAVYLVVLVSVAFMCWNMMKVLMKSKRGTLAGTGPQLQLRKSESEESRTARRQTIIFLRL 287

  Fly   303 VVITFFVCWFPFHLQRLIFLYAKNMD---NYLDINEALFSIAGFAYYVSCTVNPIVYSVMSRRYR 364
            :|:|..|||.|..::|::.......|   :|......|...:...:|:|..|||::|:|.|:::|
  Rat   288 IVVTLAVCWMPNQIRRIMAAAKPKHDWTKSYFKAYMILLPFSDTFFYLSSVVNPLLYNVSSQQFR 352

  Fly   365 VAFRELLC----------GKAVGAYYNSGFARDHSSFRESSAYDRVHSVHVRASQHPNKFETDSS 419
            ..|.::||          .|...||:        ||.:.||...|...:.: ||:..|   :.|.
  Rat   353 KVFWQVLCCRLTLQHANQEKQQRAYF--------SSTKNSSRSARSPLIFL-ASRRSN---SSSR 405

  Fly   420 SANRVLIKKTYSL----------PLPKNADSTVLSTTDIVIVLENS 455
            ..|:|.: .|:..          ||...:..|...|.......|||
  Rat   406 RTNKVFL-STFQAEAKPLEGEHQPLSPESPQTGSETKPAGSATENS 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tmA_capaR	83..367	CDD:320262	75/312 (24%)
		TM helix 2	103..129	CDD:320262	10/26 (38%)
		TM helix 3	142..172	CDD:320262	10/29 (34%)
		TM helix 4	184..206	CDD:320262	5/21 (24%)
		TM helix 5	237..266	CDD:320262	7/48 (15%)
		TM helix 6	291..321	CDD:320262	9/29 (31%)
		TM helix 7	335..360	CDD:320262	8/24 (33%)
Gpr39	NP_001107864.1	7tmA_GPR39	31..355	CDD:320263	78/326 (24%)
		TM helix 1	31..58	CDD:320263	6/26 (23%)
		TM helix 2	68..94	CDD:320263	10/25 (40%)
		TM helix 3	108..138	CDD:320263	10/29 (34%)
		TM helix 4	150..172	CDD:320263	5/21 (24%)
		TM helix 5	217..246	CDD:320263	5/28 (18%)
		TM helix 6	276..306	CDD:320263	9/29 (31%)
		TM helix 7	323..348	CDD:320263	8/24 (33%)