Protein Alignment CapaR and GHSR

DIOPT Version :10

• Sequence 1: NP_996140.1
• Gene: CapaR / 40393
• FlyBaseID: FBgn0037100
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_940799.1
• Gene: GHSR / 2693
• HGNCID: 4267
• Length: 366
• Species: Homo sapiens
• Alignment Length: 353
• Identity: 115/353 - (32%)
• Similarity: 178/353 - (50%)
• Gaps: 43/353 - (12%)

  Fly    46 FNCSPKEFVAF----------------VLGPQTLPLYKAVL---ITIIFGGIFITGVVGNLLVCI 91
            :|.:|.|...|                .||.:.|.|:.|.|   :|.....:|:.|:.||||..:
Human     2 WNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTML 66

  Fly    92 VIIRHSAMHTATNYYLFSLAVSDLLYLLFGLPTEVFLYWHQYPDLFGMPFCKIRAFISEACTYVS 156
            |:.|...:.|.||.||.|:|.||||..|. :|.::...|...|..||...||:..|:||:|||.:
Human    67 VVSRFRELRTTTNLYLSSMAFSDLLIFLC-MPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYAT 130

  Fly   157 VFTIVAFSMERFLAICHPLHLYAMVGFKRAIRIITALWIVSFISAIPFGLLSDIQYLN--YPLDH 219
            |.||.|.|:||:.|||.||....:|...|...:|..:|.|:|.||.|..:|..:::.|  .|.|.
Human   131 VLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDT 195

  Fly   220 SRIEESAFCSMSPKIVNEIPVFEVSFCIFFVIPMILIILLYGRMGAKI--RSRTNQKLGVQQGTN 282
            :....:.|...|..:.  :.|:..|  |||.:|:..:.:||..:|.|:  |.|.:..:|......
Human   196 NECRPTEFAVRSGLLT--VMVWVSS--IFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQ 256

  Fly   283 NRETRNSQMRKKTVIRMLAAVVITFFVCWFPFHLQRLIFLYAKNMD----NYLDINEALFSIAGF 343
            |.         |..::|||.||..|.:||.|||:.|  :|::|:.:    ....|::....::..
Human   257 NH---------KQTVKMLAVVVFAFILCWLPFHVGR--YLFSKSFEPGSLEIAQISQYCNLVSFV 310

  Fly   344 AYYVSCTVNPIVYSVMSRRYRVAFRELL 371
            .:|:|..:|||:|::||::||||...||
Human   311 LFYLSAAINPILYNIMSKKYRVAVFRLL 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tmA_capaR	83..367	CDD:320262	99/291 (34%)
		TM helix 2	103..129	CDD:320262	12/25 (48%)
		TM helix 3	142..172	CDD:320262	16/29 (55%)
		TM helix 4	184..206	CDD:320262	8/21 (38%)
		TM helix 5	237..266	CDD:320262	9/28 (32%)
		TM helix 6	291..321	CDD:320262	13/29 (45%)
		TM helix 7	335..360	CDD:320262	6/24 (25%)
GHSR	NP_940799.1	7tmA_GHSR	44..334	CDD:320259	102/305 (33%)
		TM helix 1	44..71	CDD:320259	8/26 (31%)
		TM helix 2	78..103	CDD:320259	12/25 (48%)
		TM helix 3	116..146	CDD:320259	16/29 (55%)
		TM helix 4	158..180	CDD:320259	8/21 (38%)
		TM helix 5	209..238	CDD:320259	9/32 (28%)
		TM helix 6	256..286	CDD:320259	14/40 (35%)
		TM helix 7	302..327	CDD:320259	6/24 (25%)