DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and Olfr165

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_666677.1	Gene:	Olfr165 / 258458	MGIID:	3029999	Length:	313	Species:	Mus musculus

Alignment Length:	330	Identity:	69/330 - (20%)
Similarity:	137/330 - (41%)	Gaps:	55/330 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 PLYKAVLITIIFGGIFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFGLPTEVFL 128
            ||:......|:  .||...::||.::.|:|...:.:||.....|..|::.||:.:...:|...|.
Mouse    23 PLHTFFFSLIL--AIFFMALIGNSVMVILIYLDAQLHTPMYILLSQLSLMDLMLISTTVPQTAFN 85

  Fly   129 YWHQYPDLFGMPFCKIRAFISEACTYVSV-----FTIVAFSMERFLAICHPLHLYAMVGFKRAIR 188
            :......: .|..|.::.|.     |||:     |.:.|.:.:|::|||:||....::..|....
Mouse    86 FLSGNKSI-SMAGCGVQIFF-----YVSLLGAECFLLAAMAYDRYVAICYPLRYPILMSHKICSL 144

  Fly   189 IITALWIVSFISAIPFGLLSDIQYLNYPLDHSRIEESAFCSMSPKIV----NEIPVFE--VSFC- 246
            :....||:..:.    |::.....|::....:|.....||.: |.::    ::..:||  :.||
Mouse   145 MAAFSWILGSLD----GIIDVAAVLSFSYCGTREIPHFFCDI-PALLTISCSDTLIFEKIIFFCC 204

  Fly   247 -IFFVIPMILIILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIRMLAAVVITFFVC 310
             |..:.|::::|..|              :.|........:..|:.:..........||:.::
Mouse   205 VIMLIFPVVIVIASY--------------ICVILAVIKMASAESRHKAFATCSSHVMVVVIYY-- 253

  Fly   311 WFPFHLQRLIFLYAKNMDNYLDINEALFSIAGFAYYVSCT--VNPIVYSVMSRRYRVAFRELL-C 372
                  ...:|:|.:...:.....:.|.|    |:|...|  :||::||:.::....||.::| .
Mouse   254 ------GAAMFIYMQPSSSRSPNQDKLVS----AFYTILTPLLNPLIYSLRNKEVARAFMKVLRM 308

  Fly   373 GKAVG 377
            .||.|
Mouse   309 DKAAG 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	61/304 (20%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	56/285 (20%)
Olfr165	NP_666677.1	TM helix 7	270..295	CDD:320543	9/28 (32%)
		7tmA_OR2T-like	26..302	CDD:320543	61/314 (19%)
		TM helix 1	27..53	CDD:320543	7/27 (26%)
		TM helix 2	60..86	CDD:320543	6/25 (24%)
		TM helix 3	98..128	CDD:320543	9/34 (26%)
		TM helix 4	141..162	CDD:320543	3/24 (13%)
		TM helix 5	196..226	CDD:320543	9/43 (21%)
		TM helix 6	233..263	CDD:320543	5/37 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000